Table 4: Clinical features of the 21 infants with severe lower respiratory tract infection

Patient no.	Region	Age, mo	< 36 weeks' gestational age	Underlying risk factor(s) for severe RSV infection	Length of hospital stay, d	Duration of mechanical ventilation, d	Complications during hospital stay	Infectious agents identified
1	Northwest Territories	3-6	Yes	No	57	12	Necrosis of lung necessitating pneumonectomy, bacterial sepsis	RSV, rhinovirus/enterovirus
2	Nunavut	< 3	No	No	25	17	Bacterial sepsis	RSV, Bordetella pertussis
3	Nunavut	< 3	No	No	32	9	Required inotropes	RSV, B. pertussis
4		< 12	No	No	1	1	Bilateral necrotizing pneumonia, bacterial sepsis, acute renal failure; died during transport	Staphylococcus aureus
5	Nunavut	< 3	No	No	2	1	-	RSV
6	Nunavut	< 3	No	No	5	1	Required cardiopulmonary resuscitation	Negative
7	Nunavut	3-6	Yes	No	19	9	-	Rhinovirus/enterovirus
8	Nunavut	< 3	No	No	31	30	Required HFVO	RSV, adenovirus
9	Nunavut	< 3	No	No	41	16	Required HFVO	RSV, rhinovirus/enterovirus
10	Nunavut	3-6	Yes	Yes	216	32	Required HFVO	RSV, rhinovirus/enterovirus, influenza A (H1N1)
11	Nunavut	< 3	Yes	No	14	3	-	Negative
12	Nunavut	< 3	No	No	15	3	-	RSV
13	Nunavut	3-6	Yes	Yes	15	4	Required inotropes	Negative
14	Nunavut	< 12	Yes	No	17	0	Chest tube, pneumothorax	Negative
15	Nunavut	< 3	Yes	No	86	29	-	Rhinovirus/enterovirus, human coronavirus OC43
16	Nunavut	< 12	Yes	No	156	31	HFVO, bacterial sepsis	RSV, adenovirus, S. aureus (blood)
17	Nunavik	< 3	No	No	10	6	-	RSV, rhinovirus/enterovirus
18	Nunavik	< 3	Yes	No	13	2	-	Rhinovirus/enterovirus
19	Nunavik	< 3	No	No	24	12	-	RSV
20	Nunavik	< 3	No	No	25	8	-	RSV
21	Nunavik	< 3	No	No	96	18	Bacterial sepsis	Influenza virus

Note: HFVO = high-frequency ventilation oscillation, RSV = respiratory syncytial virus.

*Includes preterm birth (< 36 weeks' gestational age), chronic lung disease, congenital heart disease, immunodeficiency, congenital or neurologic conditions affecting respiration.