Table 2: Key eligibility criteria for reimbursement of simeprevir with peginterferon plus ribavirin for treatment of hepatitis C virus infection, by jurisdiction
JurisdictionRestriction
Minimum fibrosis stage requiredSubstance useHIV coinfectionPrescriberDecompensated cirrhosis
Province/territory
British ColumbiaF2 None listedNone listedGeneral practitionerNone listed
AlbertaF2None listedNone listedNone listedIneligible
SaskatchewanF2None listedNone listedGeneral practitionerNone listed
ManitobaF2None listedEligibleSpecialistIneligible
OntarioF2None listedEligibleGeneral practitionerIneligible
QuebecNone listed*None listedIneligibleNone listedNone listed
New BrunswickF2None listedNone listedNone listedIneligible
Nova ScotiaF2None listedNone listedSpecialistIneligible
Prince Edward IslandNANANANANA
Newfoundland and LabradorF2None listedNone listedNone listedIneligible
YukonF2None listedNone listedSpecialistIneligible
Northwest TerritoriesF2None listedNone listedSpecialistNone listed
NunavutF2None listedNone listedSpecialistNone listed
Federal
Non-Insured Health Benefits ProgramF2None listedNone listedSpecialistNone listed
Correctional Service CanadaF2§None listed¶None listedNone listedNone listed

Note: NA = not available.

*However, coauthors indicated that in practice there were no fibrosis stage restrictions.

†However, exceptions could be granted via the "patient d'exception" (exception patient) measure.

‡None listed in criteria; however, a specialist prescription was required for peginterferon-based treatments.

§Treatment prioritized to patients with stage F3 or F4 fibrosis; treatment for those with stage F0, F1 or F2 fibrosis was reviewed on a case-by-case basis.

¶Directly observed therapy required.