Table 4: Encounter-adjusted logistic regressions for the recorded type of medications for depression by sex in patients with diagnoses of Parkinson disease and depression
Dependent variableSex
(male reference = 1.00)
No. of encounters with a
primary care provider
OR (95% CI)p valueOR (95% CI)p value
Selective serotonin reuptake inhibitors1.25 (0.90-1.73)0.21.22 (1.08-1.39)< 0.01*
Benzodiazepines and related hypnosedative1.11 (0.80-1.54)0.51.25 (1.10-1.42)< 0.001*
Atypical and antipsychotic agents1.12 (0.79-1.59)0.51.10 (0.96-1.25)0.2
Serotonin-norephinephrine reuptake inhibitors1.18 (0.77-1.83)0.41.06 (0.90-1.25)0.5
Serotonin antagonist and reuptake inhibitors0.64 (0.39-1.04)0.071.14 (0.94-1.38)0.2
Tricyclics and tetracyclics1.73 (0.99-3.10)0.061.32 (1.07-1.67)0.01*
Bipolar medications1.22 (0.69-2.16)0.51.15 (0.93-1.43)0.2
Monoamine oxidase inhibitors0.76 (0.19-2.90)0.71.23 (0.75-2.14)0.4

Note: CI = confidence intervals, OR = odds ratio.

*Significance defined as p < 0.05.

Gender served as the main independent variable and the number of encounters with a primary care provider in a 2-year period served as a covariate using a log-2 scale in the regression model.