Table 4: Ninety-day risk of a hospital encounter with acute pancreatitis in patients given sitagliptin or an alternative hypoglycemic agent,* before and after propensity weighting
VariableNo. (%) of eventsAbsolute risk difference,
% (95% CI)
Odds ratio
(95% CI)
Before weightingAfter weighting†
Sitagliptin
n = 57 689
Alternative hypoglycemic agent
n = 83 405
Sitagliptin
n = 57 689
Alternative hypoglycemic agent
n = 55 705
Hospital encounter with acute pancreatitis46(0.08)83.40(0.10)46(0.08)48(0.09)–0.01
(–0.05 to 0.02)
0.92
(0.55 to 1.55)

Note: CI = confidence interval.
*Patients prescribed glyburide, gliclazide, metformin or insulin served as the reference group.
†All patients identified before weighting were included in the analysis. The number of patients indicated represents a weighted total.