Table 1: Characteristics of included studies
StudySexMean age, yrNo. of participants*Type of intervention for prior weight lossIntervention typeControlIntervention length, mo.LocationPublication date
Champagne et al.17
Svetkey et al.18
M + F551032Six-month diet plus group-based supportLifestyle (delivery strategies: Internet or personal contact)Self-directed30US2011
Davidson et al.12M + F43306120 mg orlistat 3×/d for 1 yr plus controlled-energy diet120 mg orlistat 3×/d plus weight-maintenance dietPlacebo plus same weight-maintenance diet12US1999
Hauptman et al.13M + F42273120 mg orlistat 3×/d for 1 yr plus energy-reduced diet120 mg orlistat 3×/d plus weight-maintenance dietPlacebo plus same weight-maintenance diet12US2000
Hill et al.14M + F46369Six-month hypoenergetic diet plus encouraged to exercise120 mg orlistat 3×/d plus dietary and behavioural counsellingPlacebo plus same diet and behavioural components12US1999
Richelsen et al.15M + F47309Eight-week very low-energy diet120 mg orlistat 3×/d plus energy-restricted diet and dietary and lifestyle counsellingPlacebo plus same diet and behavioural components36Scandinavia2007
Rickel et al.19
Perri et al.20
Radcliff et al.21
F59234Six-month group-based lifestyle programSix-month group-based lifestyle programNewsletters with tips and recipes6US2011
Sjöström et al.16M + F45261120 mg orlistat 3×/d for 1 yr plus hypocaloric diet120 mg orlistat 3×/d plus weight-maintenance dietPlacebo plus weight-maintenance diet12Europe1998
Thomas et al.22Not reported4555Not reported (recruited from a weight loss clinic)Weekly emails from a dietician with dietary, behavioural and exercise adviceNo contact6UK2011

Note: F = female, M = male.
*If a study included multiple treatment arms with different doses of orlistat, only the 120 mg group was included.