Table 5: Reasons documented for not giving thrombolysis to patients with ischemic stroke presenting to Canadian hospitals during the study period, by hospital type

Reasons	Proportion of patients, %
Reasons	Comprehensive stroke centre n = 2878 N, weighted = 11036.8	Primary stroke centre n = 2707 N, weighted = 9439.1	Other n = 2399 N, weighted = 11036.6	All hospitals n = 7984 N, weighted = 31512.5
Interval from onset of symptoms to arrival > 4.5 h*	48.8	35.3	41.6	42.3
Neurological deficit judged too mild	26.6	22.0	24.3	24.4
Neurological deficit judged too severe	3.4	2.7	3.5	3.2
Clear medical contraindication	6.6	4.3	3.4	4.8
Delayed decision	0.2	0.3	0.3	0.3
Documented physician decision	6.4	8.0	5.3	6.5
Not documented	20.0	29.7	26.9	25.3

*During the study period, guidelines changed from a 3-hour window for stroke thrombolysis to a 4.5-hour window based on new randomized trials. Thus, the proportion of patients who received treatment may be appropriately conservative.