Table 4: Factors associated with in-hospital and 90-day postdischarge mortality
VariableIn-hospital mortalityPostdischarge mortality (90 d)
Adjusted HR* (95% CI)p valueAdjusted HR† (95% CI)p value
Age, yr
< 60 (ref)1.00 (ref)
61–701.24 (0.79–1.95)0.4
71–802.30 (1.53–3.47)< 0.0001
> 804.22 (2.89–6.17)< 0.0001
Methicillin resistance
No1.00 (ref)
Yes 1.74 (1.04–2.89)0.03
Sepsis
No1.00 (ref)
Yes 1.44 (1.04–1.99)0.03
Admission to intensive care unit
No1.00 (ref)
Yes2.35 (1.78–3.11) < 0.0001
Hepatic failure
No 1.00 (ref)1.00 (ref)
Yes2.20 (1.25–3.88)0.015.42 (1.60–18.35) 0.01
Prolonged ventilation > 21 d
No
Yes
Cerebrovascular disease
No1.00 (ref)
Yes2.16 (1.21–3.86) 0.01
COPD
No1.00 (ref)
Yes2.43 (1.28–4.61)0.01
Metastatic cancer
No 1.00 (ref)1.00 (ref)
Yes2.79 (1.90–4.10) < 0.00015.32 (2.80–10.07) < 0.0001

Note: CI = confidence interval, COPD = chronic obstructive pulmonary disorder, HR = hazard ratio, ref = reference.
*Adjusted for age, sepsis, admission to the intensive care unit, hepatic failure and metastatic cancer.
†Adjusted for methicillin resistance, hepatic failure, cerebrovascular disease, COPD and metastatic cancer.