| Outcome | No. (%) of patients |
|---|---|
| Recurrent S. aureus bacteremia infection | 189 (20.4) |
| One recurrence | 161 (17.4) |
| Two recurrences | 14 (1.5) |
| Three or more recurrences | 14 (1.5) |
| Complicated S. aureus bacteremia | 248 (26.8) |
| Infective endocarditis | 72 (7.8) |
| Septic arthritis | 28 (3.0) |
| Deep tissue abscess | 56 (6.0) |
| Osteomyelitis | |
| Vertebral | 25 (2.7) |
| Nonvertebral (i.e., hand or foot) | 6 (0.6) |
| Epidural abscess | 22 (2.4) |
| Septic thrombophlebitis | 2 (0.2) |
| Psoas abscess | 12 (1.3) |
| Meningitis | 4 (0.4) |
| Embolic stroke | 8 (0.9) |
| Other complications* | 13 (1.4) |
| Complications during hospital stay | |
| Operative intervention | 258 (27.9) |
| Renal failure requiring dialysis | 80 (8.6) |
| Hepatic failure | 23 (2.5) |
| Prolonged ventilation (> 21 d) | 58 (6.3) |
| Clostridium difficile infection | 22 (2.4) |
| Ischemic colitis | 17 (1.8) |
| Myocardial infarction | 10 (1.1) |
| Admission to the intensive care unit | 225 (24.3) |
| All-cause mortality† | 258 (27.9) |
| In-hospital mortality | 196 (21.1) |
| Postdischarge mortality (0–30 d) | 30 (3.2) |
| Postdischarge mortality (31–90 d) | 32 (3.5) |
| Mortality after 90 d postdischarge | 94 (10.2) |
*Includes patients with mycotic aneurysm (n = 7), empyema (n = 4) and pericarditis (n = 2). †Defined as all mortalities that occurred in hospital and up to 90 days postdischarge.