| Variable | Breast cancer–specific survival | Overall survival | ||
|---|---|---|---|---|
| Hazard ratio (95% CI) | Hazard ratio (95% CI) | |||
| Age, per yr | 1.02 | (1.00–1.03) | 1.06 | (1.05–1.07) |
| Grade | ||||
| 2 v. 1 | 2.0 | (1.3–2.9) | 1.3 | (1.0–1.6) |
| 3 v. 1 | 3.5 | (2.3–5.2) | 1.9 | (1.5–2.4) |
| LVI, positive v. negative | 1.6 | (1.2–2.0) | 1.5 | (1.2–1.8) |
| Stage | ||||
| II v. I | 3.0 | (2.2–4.3) | 1.5 | (1.2–1.8) |
| III v. I | 9.8 | (6.5–14.7) | 4.0 | (3.1–5.2) |
| IV v. I | 47.0 | (30.6–73.1) | 15.5 | (11.0–22.0) |
| Radiotherapy* | 0.76 | (0.60–0.96) | 0.68 | (0.60–0.80) |
| Chemotherapy* | 0.58 | (0.43–0.78) | NA | NA |
| Hormone therapy* | 0.74 | (0.59–0.95) | 0.70 | (0.59–0.83) |
Note: CI = confidence interval, LVI = lymphatic vascular space invasion, NA = not applicable. *Within 1 year of diagnosis, expressed as the hazard ratio of having had treatment v. not having had treatment.