Table 2: Characteristics of 1119 patients at enrolment in the Canadian Co-infection Cohort

Characteristic	Proportion of patients*
Characteristic	Spontaneous HCV clearance n = 100	HCV treatment before or at enrolment n = 184	No follow-up after enrolment n = 154	No HCV treatment during follow-up n = 518	HCV treatment during follow-up n = 163
Age, yr, median	45	46	45	44	44
Female	0.41	0.22	0.24	0.28	0.17
Aboriginal	0.23	0.12	0.17	0.17	0.07
HCV genotype 1	0.14	0.61	0.57	0.62	0.62
HCV genotype 2, 3	0.09	0.28	0.21	0.15	0.25
HCV genotype unknown	0.77	0.08	0.21	0.21	0.10
Chronic hepatitis B virus† infection	0.06	0.05	0.09	0.07	0.03
Not taking antiretroviral therapy	0.19	0.10	0.21	0.22	0.20
CD4 cell count, cells/uL, median	370	420	400	360	400
Duration of HCV infection, yr , median	19	17	19	19	16
APRI‡	0.33	0.68	0.67	0.61	0.94
End-stage liver disease§	0.04	0.20	0.08	0.08	0.09
Ever used crack or cocaine	0.72	0.60	0.82	0.75	0.57
Psychiatric diagnosis¶	0.58	0.49	0.54	0.48	0.49
Currently homeless	0.15	0.04	0.19	0.14	0.11
Current alcohol use	0.45	0.47	0.59	0.51	0.51

Note: HCV = hepatitis C virus, APRI = aspartate aminotransferase to platelet ratio index. *Unless otherwise stated  †Chronic hepatitis B virus infection was determined by the presence of hepatitis B surface antigen in serum. ‡APRI is a surrogate marker for liver fibrosis: an APRI score ≥ 1.5 indicates substantial liver fibrosis; a score ≥ 2 indicates cirrhosis. §Diagnosis of ascites, portal hypertension, spontaneous bacterial peritonitis, encephalopathy, esophageal varices or hepatocellular carcinoma; data were collected by use of dedicated case-report forms and were centrally validated. ¶Diagnosis in medical records of depression, bipolar disorder, schizophrenia or personality disorder; or a patient report of past psychiatric hospital admission.