PT  - JOURNAL ARTICLE
AU  - Corinne M. Hohl
AU  - Rhonda J. Rosychuk
AU  - Andrew D. McRae
AU  - Steven C. Brooks
AU  - Patrick Archambault
AU  - Patrick T. Fok
AU  - Philip Davis
AU  - Tomislav Jelic
AU  - Joel P. Turner
AU  - Brian H. Rowe
AU  - Éric Mercier
AU  - Ivy Cheng
AU  - John Taylor
AU  - Raoul Daoust
AU  - Robert Ohle
AU  - Gary Andolfatto
AU  - Clare Atzema
AU  - Jake Hayward
AU  - Jaspreet K. Khangura
AU  - Megan Landes
AU  - Eddy Lang
AU  - Ian Martin
AU  - Rohit Mohindra
AU  - Daniel K. Ting
AU  - Samuel Vaillancourt
AU  - Michelle Welsford
AU  - Baljeet Brar
AU  - Tara Dahn
AU  - Hana Wiemer
AU  - Krishan Yadav
AU  - Justin W. Yan
AU  - Maja Stachura
AU  - Colleen McGavin
AU  - Jeffrey J. Perry
AU  - Laurie J. Morrison
ED  - ,
TI  - Development of the Canadian COVID-19 Emergency Department Rapid Response Network population-based registry: a methodology study
AID  - 10.9778/cmajo.20200290
DP  - 2021 Jan 01
TA  - CMAJ Open
PG  - E261--E270
VI  - 9
IP  - 1
4099  - http://www.cmajopen.ca/content/9/1/E261.short
4100  - http://www.cmajopen.ca/content/9/1/E261.full
SO  - CMAJ2021 Jan 01; 9
AB  - Background: Emergency physicians lack high-quality evidence for many diagnostic and treatment decisions made for patients with suspected or confirmed coronavirus disease 2019 (COVID-19). Our objective is to describe the methods used to collect and ensure the data quality of a multicentre registry of patients presenting to the emergency department with suspected or confirmed COVID-19.Methods: This methodology study describes a population-based registry that has been enrolling consecutive patients presenting to the emergency department with suspected or confirmed COVID-19 since Mar. 1, 2020. Most data are collected from retrospective chart review. Phone follow-up with patients at 30 days captures the World Health Organization clinical improvement scale and contextual, social and cultural variables. Phone follow-up also captures patient-reported quality of life using the Veterans Rand 12-Item Health Survey at 30 days, 60 days, 6 months and 12 months. Fifty participating emergency departments from 8 provinces in Canada currently enrol patients into the registry.Interpretation: Data from the registry of the Canadian COVID-19 Emergency Department Rapid Response Network will be used to derive and validate clinical decision rules to inform clinical decision-making, describe the natural history of the disease, evaluate COVID-19 diagnostic tests and establish the real-world effectiveness of treatments and vaccines, including in populations that are excluded or underrepresented in clinical trials. This registry has the potential to generate scientific evidence to inform our pandemic response, and to serve as a model for the rapid implementation of population-based data collection protocols for future public health emergencies.Trial registration: Clinicaltrials.gov, no. NCT04702945