TY - JOUR T1 - Psychiatric morbidity and cervical cancer screening: a retrospective population-based case–cohort study JF - CMAJ Open JO - CMAJ SP - E134 LP - E141 DO - 10.9778/cmajo.20190184 VL - 8 IS - 1 AU - Michael Ouk AU - Jodi D. Edwards AU - Jessica Colby-Milley AU - Alexander Kiss AU - Walter Swardfager AU - Marcus Law Y1 - 2020/01/01 UR - http://www.cmajopen.ca/content/8/1/E134.abstract N2 - Background: Cervical cancer screening reduces disease-specific mortality. This study aimed to estimate whether bipolar disorder or schizophrenia is associated with disparities in cervical cancer screening rates.Methods: This was a retrospective population-based matched case–cohort study of community-dwelling women aged 19–69 in Ontario using linked health administrative databases. We used odds ratios (ORs), hazards ratios and rate ratios (RRs) adjusted for demographic characteristics and relevant comorbidities to compare cervical cancer screening outcomes between women with a diagnosis of bipolar disorder or schizophrenia to women without that history matched on key demographic characteristics, between 2003 and 2015.Results: In total, 1 245 457 women were identified for inclusion in the analyses, 119 948 with a diagnosis of bipolar disorder or schizophrenia, and 1 125 509 without. Over a median follow-up duration of 12.5 years, women with the exposure were 36% less likely to be screened (OR 0.64, 95% confidence interval [CI] 0.64–0.65) than those without, and they took longer to undergo screening (median 18.98 mo v. 16.63 mo; χ2 = 3718.2, p < 0.001). They were also screened less frequently (median 6.16 yr v. 4.69 yr per screen; RR 0.85, 95% CI 0.84–0.85). These effects were consistent after we excluded the 86 475 women (6.9%) with suspected major depressive disorder, and they were larger for the 59 141 women (4.7%) not attached to a family physician.Interpretation: Women with bipolar disorder or schizophrenia were less likely to undergo cervical cancer screening, their screening was delayed, and they were screened at a lower rate compared to women without this psychiatric history. This practice gap suggests a need to further address barriers to screening, including access to a family physician, among women with bipolar disorder or schizophrenia. ER -