PT - JOURNAL ARTICLE AU - Henry H. Nguyen AU - Mark G. Swain AU - Philip Wong AU - Stephen E. Congly TI - Canadian regulations and legal ramifications for hepatic encephalopathy: a descriptive analysis AID - 10.9778/cmajo.20180024 DP - 2018 Oct 01 TA - CMAJ Open PG - E575--E579 VI - 6 IP - 4 4099 - http://www.cmajopen.ca/content/6/4/E575.short 4100 - http://www.cmajopen.ca/content/6/4/E575.full SO - CMAJ2018 Oct 01; 6 AB - Background: Hepatic encephalopathy, a form of brain dysfunction seen in the setting of liver insufficiency, negatively affects driving performance and so is both a patient and public safety issue. We aimed to review the motor vehicle codes in each Canadian province and territory relating to the reporting of patients with hepatic encephalopathy and to search a Canadian legal database for cases of motor vehicle collisions involving patients with hepatic encephalopathy.Methods: In this descriptive analysis, the transportation agencies of each Canadian province and territory were contacted via telephone and/or email between April and August 2017. Requirements of physicians to report medical conditions (including liver disease and hepatic encephalopathy) affecting a patient’s fitness to drive were assessed. WestlawNext Canada was searched for any Canadian cases on hepatic encephalopathy and driving-related lawsuits from inception to Dec. 31, 2017.Results: Reporting of medically unfit drivers is a requirement in all Canadian provinces and territories except Alberta, Quebec and Nova Scotia. Hepatic encephalopathy, cirrhosis and advanced liver disease were not specifically identified as reportable medical conditions in any province or territory. Our search did not identify any lawsuits involving a motor vehicle collision in Canada that were made either against physicians caring for patients with hepatic encephalopathy or against such patients themselves.Interpretation: Although hepatic encephalopathy has a substantial impact on driving performance, it is not specifically identified as a reportable medical condition in Canada. Increasing awareness of the potential impact of hepatic encephalopathy on safe driving for health care providers and the public is critical.