TY - JOUR T1 - Factors influencing practice variation in the management of nephrotic syndrome: a qualitative study of pediatric nephrology care providers JF - CMAJ Open SP - E424 LP - E430 DO - 10.9778/cmajo.20160078 VL - 5 IS - 2 AU - Susan M. Samuel AU - Rachel Flynn AU - Michael Zappitelli AU - Allison Dart AU - Rulan Parekh AU - Maury Pinsk AU - Cherry Mammen AU - Andrew Wade AU - Shannon D. Scott AU - for the Canadian Childhood Nephrotic Syndrome Project Team* Y1 - 2017/04/01 UR - http://www.cmajopen.ca/content/5/2/E424.abstract N2 - Background: Treatment protocols for childhood nephrotic syndrome are highly variable between providers and care centres. We conducted a qualitative study to understand the complex multilevel processes that lead to practice variation and influence provider management of nephrotic syndrome.Methods: Focus groups with multidisciplinary pediatric nephrology care providers (n = 67) from 10 Canadian pediatric nephrology centres that had more than 1 pediatric nephrologist were conducted between September 2013 and April 2015. Focus group discussions were guided by the Ottawa Model for Research Use. We used a semistructured interview guide to elicit participants' perspectives regarding 1) the work setting and context of the clinical environment, 2) reasons for variation at the provider level and 3) clinical practice guidelines for nephrotic syndrome. Focus group discussions were transcribed and analyzed concurrently with the use of qualitative content analysis.Results: Emerging themes were grouped into 2 categories: centre-level factors and provider-level factors. At the centre level, the type of care model used, clinic structures and resources, and lack of communication and collaboration within and between Canadian centres influenced care variation. At the provider level, use of experiential knowledge versus empirical knowledge and interpretation of patient characteristics influenced provider management of nephrotic syndrome.Interpretation: Centre- and provider-level factors play an important role in shaping practice differences in the management of childhood nephrotic syndrome. Further research is needed to determine whether variation in care is associated with disparities in outcomes. ER -