TY - JOUR T1 - Cancer incidence attributable to red and processed meat consumption in Alberta in 2012 JF - CMAJ Open SP - E768 LP - E775 DO - 10.9778/cmajo.20160036 VL - 4 IS - 4 AU - Anne Grundy AU - Abbey E. Poirier AU - Farah Khandwala AU - Alison McFadden AU - Christine M. Friedenreich AU - Darren R. Brenner Y1 - 2016/12/13 UR - http://www.cmajopen.ca/content/4/4/E768.abstract N2 - Background: Consumption of red and processed meats has been associated with an increased risk of colorectal cancer. The purpose of this study was to estimate the proportion and absolute number of cancers in Alberta in 2012 that could be attributed to the consumption of red and processed meat.Methods: The number and proportion of colorectal cancers in Alberta that were attributable to red and processed meat consumption were estimated using population attributable risk. Relative risks were obtained from the World Cancer Research Fund's 2011 Continuous Update Project on Colorectal Cancer, and the prevalence of red and processed meat consumption was estimated using dietary data from Alberta's Tomorrow Project. Age- and sex-specific colorectal cancer incidence data for 2012 were obtained from the Alberta Cancer Registry.Results: Among participants in Alberta's Tomorrow Project, 41%-61% of men and 14%-25% of women consumed more than 500 g of red and processed meat per week, which exceeds World Cancer Research Fund cancer prevention guidelines. For red meat consumption, population attributable risks for colorectal cancer were substantially higher for men (13.6%-17.9%) than for women (1.6%-2.1%). For processed meat consumption, the population attributable risks were also higher for men (3.2%-4.8%) than for women (1.5%-2.1%). Overall, about 12% of colorectal cancers, or 1.5% of all cancers, in Alberta in 2012 were attributable to the consumption of red and processed meat.Interpretation: Red and processed meat consumption is estimated to acount for about 12% of colorectal cancers in Alberta. Decreasing its consumption has the potential to reduce to Alberta's cancer burden. ER -