RT Journal Article
SR Electronic
T1 Incidence of delirium after cardiac surgery: protocol for the DELIRIUM-CS Canada cross-sectional cohort study
JF CMAJ Open
FD Canadian Medical Association
SP E565
OP E569
DO 10.9778/cmajo.20160136
VO 5
IS 3
A1 The DELIRIUM-CS Investigators*
A1 the Canadian Cardiovascular Critical Care Society Investigator Group and the Canadian Critical Care Trials Group
YR 2017
UL http://www.cmajopen.ca/content/5/3/E565.abstract
AB Background: Delirium is a recognized complication of cardiac surgery and is the focus of increasing attention owing to its negative effect on postoperative outcomes. However, little is known about the actual incidence of delirium following cardiac surgery, with published rates ranging widely, from 3%-78%. We describe the protocol for the DELIRIUM-CS Canada study, which will use validated and easily implementable bedside tools to determine the incidence of postoperative delirium in a contemporary cardiac surgery population. We hypothesize that delirium, identified through a systematic and standardized screening protocol, is a highly prevalent, though variable, condition following cardiac surgery.Methods: The DELIRIUM-CS Canada study is a multicentre cross-sectional cohort study. Over a 3-month period, all patients undergoing major cardiac surgical procedures at 10 participating centres will be screened for postoperative delirium by means of the Intensive Care Delirium Screening Checklist or the Confusion Assessment Method for the Intensive Care Unit. Delirium screening will be conducted for 7 days following the date of surgery or until the initial discharge from the intensive care unit. In addition to reporting an overall rate of delirium, we will report unadjusted and adjusted incidence rates of delirium by institution and for the entire cohort. Risk adjustment will be performed with the use of multivariate regression modelling techniques.Interpretation: The results of this study will provide valuable insight into the true burden of delirium among patients having undergone a major cardiac surgical procedure in the current era. This is the first step in creating a multifaceted delirium prevention/treatment clinical pathway for patients undergoing cardiac surgery. Trial registration: ClinicalTrials.gov, no. NCT02206880.