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Research

Registration for deceased organ and tissue donation among Ontario immigrants: a population-based cross-sectional study

Alvin Ho-ting Li, Ngan N. Lam, Sonny Dhanani, Matthew Weir, Versha Prakash, Joseph Kim, Greg Knoll and Amit X. Garg
October 11, 2016 4 (4) E551-E561; DOI: https://doi.org/10.9778/cmajo.20160024
Alvin Ho-ting Li
Department of Epidemiology and Biostatistics (Li, Weir, Garg), Western University, London, Ont.; Division of Nephrology (Lam), University of Alberta, Edmonton, Alta.; Trillium Gift of Life Network (Dhanani, Prakash), Toronto, Ont.; Division of Critical Care (Dhanani), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Division of Nephrology (Weir, Garg), Western University, London, Ont.; Division of Nephrology (Kim), Department of Medicine, University of Toronto, Toronto, Ont.; Division of Nephrology and Ottawa Hospital Research Institute (Knoll), The Ottawa Hospital and University of Ottawa, Ottawa, Ont.; Institute for Clinical Evaluative Sciences (Garg), London, Ont.
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Ngan N. Lam
Department of Epidemiology and Biostatistics (Li, Weir, Garg), Western University, London, Ont.; Division of Nephrology (Lam), University of Alberta, Edmonton, Alta.; Trillium Gift of Life Network (Dhanani, Prakash), Toronto, Ont.; Division of Critical Care (Dhanani), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Division of Nephrology (Weir, Garg), Western University, London, Ont.; Division of Nephrology (Kim), Department of Medicine, University of Toronto, Toronto, Ont.; Division of Nephrology and Ottawa Hospital Research Institute (Knoll), The Ottawa Hospital and University of Ottawa, Ottawa, Ont.; Institute for Clinical Evaluative Sciences (Garg), London, Ont.
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Sonny Dhanani
Department of Epidemiology and Biostatistics (Li, Weir, Garg), Western University, London, Ont.; Division of Nephrology (Lam), University of Alberta, Edmonton, Alta.; Trillium Gift of Life Network (Dhanani, Prakash), Toronto, Ont.; Division of Critical Care (Dhanani), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Division of Nephrology (Weir, Garg), Western University, London, Ont.; Division of Nephrology (Kim), Department of Medicine, University of Toronto, Toronto, Ont.; Division of Nephrology and Ottawa Hospital Research Institute (Knoll), The Ottawa Hospital and University of Ottawa, Ottawa, Ont.; Institute for Clinical Evaluative Sciences (Garg), London, Ont.
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Matthew Weir
Department of Epidemiology and Biostatistics (Li, Weir, Garg), Western University, London, Ont.; Division of Nephrology (Lam), University of Alberta, Edmonton, Alta.; Trillium Gift of Life Network (Dhanani, Prakash), Toronto, Ont.; Division of Critical Care (Dhanani), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Division of Nephrology (Weir, Garg), Western University, London, Ont.; Division of Nephrology (Kim), Department of Medicine, University of Toronto, Toronto, Ont.; Division of Nephrology and Ottawa Hospital Research Institute (Knoll), The Ottawa Hospital and University of Ottawa, Ottawa, Ont.; Institute for Clinical Evaluative Sciences (Garg), London, Ont.
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Versha Prakash
Department of Epidemiology and Biostatistics (Li, Weir, Garg), Western University, London, Ont.; Division of Nephrology (Lam), University of Alberta, Edmonton, Alta.; Trillium Gift of Life Network (Dhanani, Prakash), Toronto, Ont.; Division of Critical Care (Dhanani), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Division of Nephrology (Weir, Garg), Western University, London, Ont.; Division of Nephrology (Kim), Department of Medicine, University of Toronto, Toronto, Ont.; Division of Nephrology and Ottawa Hospital Research Institute (Knoll), The Ottawa Hospital and University of Ottawa, Ottawa, Ont.; Institute for Clinical Evaluative Sciences (Garg), London, Ont.
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Joseph Kim
Department of Epidemiology and Biostatistics (Li, Weir, Garg), Western University, London, Ont.; Division of Nephrology (Lam), University of Alberta, Edmonton, Alta.; Trillium Gift of Life Network (Dhanani, Prakash), Toronto, Ont.; Division of Critical Care (Dhanani), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Division of Nephrology (Weir, Garg), Western University, London, Ont.; Division of Nephrology (Kim), Department of Medicine, University of Toronto, Toronto, Ont.; Division of Nephrology and Ottawa Hospital Research Institute (Knoll), The Ottawa Hospital and University of Ottawa, Ottawa, Ont.; Institute for Clinical Evaluative Sciences (Garg), London, Ont.
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Greg Knoll
Department of Epidemiology and Biostatistics (Li, Weir, Garg), Western University, London, Ont.; Division of Nephrology (Lam), University of Alberta, Edmonton, Alta.; Trillium Gift of Life Network (Dhanani, Prakash), Toronto, Ont.; Division of Critical Care (Dhanani), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Division of Nephrology (Weir, Garg), Western University, London, Ont.; Division of Nephrology (Kim), Department of Medicine, University of Toronto, Toronto, Ont.; Division of Nephrology and Ottawa Hospital Research Institute (Knoll), The Ottawa Hospital and University of Ottawa, Ottawa, Ont.; Institute for Clinical Evaluative Sciences (Garg), London, Ont.
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Amit X. Garg
Department of Epidemiology and Biostatistics (Li, Weir, Garg), Western University, London, Ont.; Division of Nephrology (Lam), University of Alberta, Edmonton, Alta.; Trillium Gift of Life Network (Dhanani, Prakash), Toronto, Ont.; Division of Critical Care (Dhanani), Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont.; Division of Nephrology (Weir, Garg), Western University, London, Ont.; Division of Nephrology (Kim), Department of Medicine, University of Toronto, Toronto, Ont.; Division of Nephrology and Ottawa Hospital Research Institute (Knoll), The Ottawa Hospital and University of Ottawa, Ottawa, Ont.; Institute for Clinical Evaluative Sciences (Garg), London, Ont.
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Tables

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    Table 1: Baseline characteristics of Ontario immigrants and long-term residents
    CharacteristicNo. (%) of people*Standardized difference, %†
    Immigrants (n = 1 947 646)Long-term residents (n = 9 244 570)
    Age, yr, mean ± standard deviation44.1 ± 15.547.3 ± 19.217
    Age category, yr
        16-1976 073 (3.9)599 264 (6.6)12
        20-29290 314 (14.9)1 510 757 (16.3)4
        30-39419 949 (21.6)1 380 229 (14.9)17
        40-49493 544 (25.3)1 498 785 (16.2)23
        50-59370 569 (19.0)1 657 095 (17.9)3
        60-69163 899 (8.4)1 301 436 (14.1)18
        70-7986 024 (4.4)775 156 (8.4)16
        ≥ 8047 274 (2.4)521 848 (5.6)16
    Female sex933 639 (47.9)4 841 077 (52.4)9
    Rural residence‡24 848 (1.3)1 243 904 (13.4)48
    Neighbourhood income quintile
        First (lowest)493 294 (25.3)1 618 342 (17.5)19
        Second428 901 (22.0)1 760 076 (19.0)7
        Third409 244 (21.0)1 864 728 (20.2)2
        Fourth368 900 (18.9)1 984 856 (21.5)6
        Fifth (highest)247 307 (12.7)2 016 568 (21.8)24
    Residential instability quintile
        First (lowest)604 813 (31.0)2 350 648 (25.4)13
        Second350 284 (18.0)1 969 402 (21.3)8
        Third207 937 (10.7)1 542 066 (16.7)18
        Fourth335 781 (17.2)1 636 146 (17.7)1
        Fifth (highest)433 725 (22.3)1 615 948 (17.5)12
        Missing15 106 (0.8)130 360 (1.4)6
    Ethnic concentration quintile
        First (lowest)40 269 (2.1)1 280 350 (13.8)45
        Second73 994 (3.8)1 620 959 (17.5)46
        Third125 735 (6.4)1 749 603 (18.9)38
        Fourth294 318 (15.1)1 963 863 (21.2)16
        Fifth (highest)1 398 224 (71.8)2 499 435 (27.0)100
        Missing15 106 (0.8)130 360 (1.4)6
    Dependency quintile
        First (lowest)663 665 (34.1)1 977 392 (21.4)29
        Second529 973 (27.2)2 034 206 (22.0)12
        Third335 353 (17.2)1 815 183 (19.6)6
        Fourth214 055 (11.0)1 609 352 (17.4)18
        Fifth (highest)189 494 (9.7)1 678 077 (18.2)24
        Missing15 106 (0.8)130 360 (1.4)6
    Material deprivation quintile
        First (lowest)502 397 (25.8)2 461 225 (26.6)2
        Second402 011 (20.6)2 135 074 (23.1)6
        Third377 933 (19.4)1 825 100 (19.7)1
        Fourth331 916 (17.0)1 488 359 (16.1)2
        Fifth (highest)318 283 (16.3)1 204 452 (13.0)9
        Missing15 106 (0.8)130 360 (1.4)6
    CharacteristicNo. (%) of people*Standardized difference, %†
    Immigrants (n = 1 947 646)Long-term residents (n = 9 244 570)
    World region of birth 
        East Asia and Pacific499 533 (25.6)--
        South Asia474 101 (24.3)--
        Latin America and Caribbean269 170 (13.8)--
        Eastern Europe and Central Asia215 856 (11.1)--
        Middle East and North Africa181 565 (9.3)--
        Western Europe153 259 (7.9)--
        Sub-Saharan Africa115 371 (5.9)--
        United States, Australia and New Zealand38 014 (2.0)--
        Other777 (< 0.1)--
    Education
        University degree or higher502 234 (25.8)--
        Some university80 655 (4.1)--
        Nonuniversity qualifications (e.g., college diploma)277 160 (14.2)--
        Secondary or less923 002 (47.4)--
        None164 521 (8.4)--
        Missing74 (< 0.01)--
    Time since arrival in Canada, yr
        ≥ 20512 570 (26.3)--
        15-19379 567 (19.5)--
        10-14453 966 (23.3)--
        4-9518 677 (26.6)--
        < 482 866 (4.2)--
    Language ability
        English1 149 609 (59.0)--
        French16 612 (0.8)--
        Both49 192 (2.5)--
        Neither732 166 (37.6)--
        Missing67 (< 0.01)--
    Marital status
        Married1 035 265 (53.2)--
        Separated, divorced, widowed74 680 (3.8)--
        Single837 396 (43.0)--
        Missing305 (< 0.1)--
    Immigrant class
        Economic899 634 (46.2)--
        Family685 080 (35.2)--
        Refugee312 174 (16.0)--
        Other50 750 (2.6)--
        Missing8 (< 0.01)--

    *Except for age (mean ± standard deviation).

    †Compared to long-term residents. Standardized differences greater than 10% represent a meaningful difference between the 2 groups.

    ‡Areas with a population less than 10 000.

      • View popup
      Table 2: Characteristics associated with donor registration among immigrants and long-term residents combined
      CharacteristicNo. (%) registered   Prevalence ratio (95% confidence interval)
      UnadjustedAdjusted*
      World region of birth
      Long-term residents (n = 9 244 570)2 453 116 (26.5)1.00 [Reference]1.00 [Reference]
      Immigrants (n = 1 947 646)231 180 (11.9)
          East Asia and Pacific41 752 (8.4)0.31 (0.31-0.32)0.39 (0.38-0.40)
          South Asia53 077 (11.2)0.42 (0.42-0.43)0.53 (0.52-0.54)
          Latin America and Caribbean41 006 (15.2)0.57 (0.57-0.58)0.68 (0.67-0.69)
          Eastern Europe and Central Asia20 222 (9.4)0.35 (0.35-0.36)0.38 (0.37-0.40)
          Middle East and North Africa19 059 (10.5)0.40 (0.39-0.40)0.47 (0.46-0.49)
          Western Europe31 637 (20.6)0.78 (0.77-0.79)0.79 (0.78-0.81)
          Sub-Saharan Africa9080 (7.9)0.30 (0.29-0.30)0.35 (0.33-0.36)
      United States, Australia and New Zealand15 209 (40.0)1.51 (1.49-1.53)1.40 (1.36-1.43)
          Other138 (17.8)0.67 (0.58-0.78)1.01 (0.74-1.36)
      Age category, yr
      16-19107 575 (15.9)1.00 [Reference]1.00 [Reference]
      20-29406 873 (22.6)1.42 (1.41-1.43)1.45 (1.43-1.47)
      30-39526 486 (29.2)1.84 (1.83-1.85)1.96 (1.94-1.99)
      40-49556 450 (27.9)1.75 (1.74-1.76)1.85 (1.82-1.87)
      50-59502 942 (24.8)1.56 (1.55-1.57)1.54 (1.52-1.56)
      60-69349 575 (23.9)1.50 (1.49-1.51)1.41 (1.39-1.43)
      70-79165 279 (19.2)1.20 (1.20-1.21)1.11 (1.10-1.13)
      ≥ 8069 116 (12.1)0.76 (0.76-0.77)0.69 (0.68-0.70)
      Sex
      Female1 495 776 (25.9)1.00 [Reference]1.00 [Reference]
      Male1 188 520 (21.9)0.85 (0.85-0.85)0.83 (0.83-0.83)
      Residence
      Urban2 306 304 (23.2)1.00 [Reference]1.00 [Reference]
      Rural†377 992 (29.8)1.28 (1.28-1.29)0.97 (0.96-0.98)
      Neighbourhood income quintile
      First (lowest)430 400 (20.4)0.86 (0.86-0.86)1.03 (1.02-1.04)
      Second491 648 (22.5)0.95 (0.95-0.95)1.00 (0.99-1.01)
      Third537 122 (23.6)1.00 [Reference]1.00 [Reference]
      Fourth588 534 (25.0)1.06 (1.05-1.06)1.00 (0.99-1.00)
      Fifth (highest)636 592 (28.1)1.19 (1.18-1.19)1.02 (1.01-1.02)
      Ethnic concentration quintile†
      First (lowest)417 114 (31.6)1.08 (1.08-1.08)1.11 (1.10-1.11)
      Second524 728 (31.0)1.06 (1.06-1.06)1.07 (1.06-1.07)
      Third548 379 (29.2)1.00 [Reference]1.00 [Reference]
      Fourth582 938 (25.8)0.88 (0.88-0.89)0.89 (0.89-0.89)
      Fifth (highest)575 086 (14.8)0.50 (0.50-0.51)0.58 (0.57-0.58)
      Material deprivation quintile†
      First (lowest)772 427 (26.1)1.11 (1.10-1.11)1.10 (1.10-1.11)
      Second625 442 (24.7)1.05 (1.04-1.05)1.02 (1.01-1.03)
      Third519 271 (23.6)1.00 [Reference]1.00 [Reference]
      Fourth414 418 (22.3)0.97 (0.96-0.97)1.00 (0.99-1.01)
      Fifth (highest)316 687 (20.8)0.88 (0.88-0.89)0.99 (0.98-1.01)

      *Adjusted for world region of birth, sex, residence, age category, neighbourhood income quintile, material deprivation quintile and ethnic concentration quintile. Adjusted analysis based on a random sample of 20% (n = 2 238 443).

      †Data missing for 145 466 people (1.3%), of whom 36 051 were registered for donor and tissue donation.

        • View popup
        Table 3: Characteristics associated with donor registration among immigrants
        CharacteristicNo. (%) registered*Prevalence ratio (95% confidence interval)
        UnadjustedAdjusted†
        World region of birth
            East Asia and Pacific41 748 (8.4)0.21 (0.21-0.21)0.28 (0.27-0.28)
            South Asia53 066 (11.2)0.28 (0.28-0.28)0.37 (0.36-0.38)
            Latin America and Caribbean40 985 (15.2)0.38 (0.38-0.39)0.51 (0.50-0.52)
            Eastern Europe and Central Asia20 216 (9.4)0.23 (0.23-0.24)0.28 (0.27-0.28)
            Middle East and North Africa19 056 (10.5)0.26 (0.26-0.27)0.33 (0.32-0.33)
            Western Europe31 634 (20.6)0.52 (0.51-0.52)0.57 (0.56-0.58)
            Sub-Saharan Africa9 078 (7.9)0.20 (0.19-0.20)0.26 (0.26-0.27)
        United States, Australia and New Zealand15 207 (40.0)1.00 [Reference]1.00 [Reference]
            Other138 (17.8)0.44 (0.38-0.52)0.58 (0.50-0.67)
        Age category, yr
            16-194 545 (6.0)1.00 [Reference]1.00 [Reference]
            20-2931 791 (11.0)1.83 (1.78-1.89)1.85 (1.80-1.91)
            30-3957 841 (13.8)2.31 (2.24-2.37)2.23 (2.16-2.30)
            40-4968 319 (13.8)2.32 (2.25-2.39)2.02 (1.95-2.08)
            50-5944 244 (11.9)2.00 (1.94-2.06)1.76 (1.70-1.82)
            60-6916 302 (9.9)1.66 (1.61-1.72)1.57 (1.52-1.63)
            70-795 931 (6.9)1.15 (1.11-1.20)1.28 (1.23-1.33)
            ≥ 802 155 (4.6)0.76 (0.73-0.80)0.88 (0.84-0.93)
        Sex
            Female121 402 (12.0)1.00 [Reference]1.00 [Reference]
            Male109 726 (11.8)0.98 (0.97-0.99)0.93 (0.93-0.94)
        Residence
            Urban224 266 (11.7)1.00 [Reference]1.00 [Reference]
            Rural6 862 (28.3)2.43 (2.38-2.48)1.24 (1.21-1.26)
        Neighbourhood income quintile
            First (lowest)43 634 (8.8)0.73 (0.72-0.74)0.96 (0.94-0.97)
            Second46 543 (10.9)0.90 (0.89-0.91)1.00 (0.99-1.01)
            Third49 520 (12.1)1.00 [Reference]1.00 [Reference]
            Fourth49 308 (13.4)1.10 (1.09-1.12)1.09 (1.08-1.11)
            Fifth (highest)42 123 (17.0)1.41 (1.39-1.42)1.02 (1.00-1.03)
        Ethnic concentration quintile‡
            First (lowest)9 435 (23.4)1.27 (1.25-1.30)1.12 (1.10-1.15)
            Second15 272 (20.6)1.12 (1.10-1.14)1.06 (1.04-1.08)
            Third23 119 (18.4)1.00 [Reference]1.00 [Reference]
            Fourth43 565 (14.8)0.81 (0.79-0.82)0.88 (0.86-0.89)
            Fifth (highest)137 715 (9.9)0.54 (0.53-0.54)0.70 (0.69-0.71)
        CharacteristicNo. (%) registered*Prevalence ratio (95% confidence interval)
        UnadjustedAdjusted†
        Material deprivation quintile‡
            First (lowest)72 247 (14.4)1.23 (1.21-1.24)1.09 (1.08-1.10)
            Second52 4a77 (13.1)1.11 (1.10-1.13)1.04 (1.03-1.05)
            Third44 268 (11.9)1.00 [Reference]1.00 [Reference]
            Fourth33 461 (10.1)0.86 (0.85-0.87)0.92 (0.91-0.93)
            Fifth (highest)26 653 (8.4)0.71 (0.70-0.73)0.82 (0.80-0.83)
        Education§
            University degree or higher71 901 (14.3)1.00 [Reference]1.00 [Reference]
            Some university11 142 (13.8)0.97 (0.95-0.98)0.96 (0.95-0.98)
        Nonuniversity qualifications (e.g., college diploma)36 403 (13.1)0.92 (0.91-0.93)0.92 (0.91-0.93)
            Secondary or less95 818 (10.4)0.73 (0.72-0.73)0.78 (0.77-0.79)
            None15 864 (9.6)0.67 (0.66-0.68)0.81 (0.80-0.83)
        Time since arrival in Canada, yr
            ≥ 2056 371 (11.0)1.23 (1.21-1.26)1.31 (1.28-1.35)
            15-1953 046 (14.0)1.57 (1.53-1.61)1.76 (1.72-1.80)
            10-1460 633 (13.4)1.50 (1.47-1.53)1.66 (1.62-1.70)
            4-953 695 (10.4)1.16 (1.14-1.19)1.21 (1.18-1.23)
            < 47 383 (8.9)1.00 [Reference]1.00 [Reference]
        Language ability§
            English160 835 (14.0)1.00 [Reference]1.00 [Reference]
            French1 305 (7.9)0.56 (0.53-0.59)0.66 (0.63-0.70)
            Both7 704 (15.7)1.12 (1.10-1.14)1.06 (1.04-1.08)
            Neither61 284 (8.4)0.60 (0.59-0.60)0.76 (0.75-0.77)
        Marital status§
            Married121 619 (11.7)1.00 [Reference]1.00 [Reference]
            Separated, divorced, widowed6 876 (9.2)0.78 (0.77-0.80)1.06 (1.04-1.09)
            Single102 633 (12.3)1.04 (1.04-1.05)1.11 (1.10-1.12)
        Immigrant class§
            Economic119 029 (13.2)1.00 [Reference]1.00 [Reference]
            Family74 731 (10.9)0.82 (0.82-0.83)0.86 (0.86-0.87)
            Refugee31 305 (10.0)0.76 (0.75-0.77)0.95 (0.94-0.96)
            Other6 063 (11.9)0.90 (0.88-0.93)0.96 (0.93-0.98)

        *Total number of immigrants for this analysis was 1 947 192, of whom 231 128 were registered for organ and tissue donation; 454 immigrants, of whom 52 were registered, had missing data on immigration-related characteristics and were excluded from this cohort.

        †Adjusted for world region of birth, sex, residence, age category, neighbourhood income quintile, material deprivation quintile, ethnic concentration quintile, education, time since arrival in Canada, language ability, marital status and immigrant class.

        ‡Data missing for 15 102 people (< 1.0%), of whom 2022 were registered.

        §Data missing for 454 people (< 0.01%), of whom 52 were registered, who were then further excluded from analysis.

          • View popup
          Table 4: Characteristics associated with donor registration among immigrants from the 5 countries with the highest numbers of unregistered immigrants
          CharacteristicAdjusted prevalence ratio (95% confidence interval)*
          IndiaChinaPhilippinesPakistanSri Lanka
          Age category, yr
              16-191.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]
              20-291.57 (1.44-1.71)1.64 (1.43-1.88)1.74 (1.55-1.97)2.1 (1.78-2.48)1.87 (1.61-2.18)
              30-391.69 (1.55-1.85)1.41 (1.21-1.63)1.85 (1.63-2.10)2.1 (1.76-2.51)2.09 (1.79-2.44)
              40-491.85 (1.69-2.02)1.28 (1.10-1.48)1.44 (1.26-1.65)2.18 (1.82-2.61)1.75 (1.49-2.04)
              50-591.71 (1.56-1.87)1.17 (1.01-1.37)1.10 (0.96-1.27)2.37 (1.96-2.87)1.44 (1.23-1.7)
              60-691.40 (1.27-1.54)1.08 (0.92-1.28)0.83 (0.71-0.97)2.56 (2.08-3.14)1.26 (1.06-1.49)
              70-791.19 (1.07-1.32)0.85 (0.71-1.01)0.54 (0.44-0.66)2.37 (1.83-3.09)1.3 (1.08-1.56)
              ≥ 800.94 (0.82-1.08)0.58 (0.47-0.71)0.38 (0.29-0.49)2.3 (1.59-3.33)0.94 (0.75-1.17)
          Sex
              Female1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]
              Male1.01 (0.99-1.03)1.03 (0.99-1.06)0.81 (0.78-0.84)1.09 (1.03-1.15)1.04 (1.00-1.08)
          Residence
              Urban1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]
              Rural†1.09 (0.96-1.23)1.22 (0.98-1.52)1.38 (1.16-1.65)1.41 (1.02-1.93)1.11 (0.83-1.48)
          Neighbourhood income quintile
              First (lowest)0.90 (0.87-0.94)1.1 (1.04-1.18)0.90 (0.85-0.97)0.89 (0.80-0.98)0.99 (0.93-1.06)
              Second0.95 (0.92-0.98)1.01 (0.95-1.06)0.96 (0.91-1.01)1.04 (0.96-1.13)0.96 (0.92-1.01)
              Third1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]
              Fourth1.04 (1.01-1.07)1.04 (0.99-1.1)1.05 (0.99-1.11)0.96 (0.89-1.04)1.00 (0.95-1.06)
              Fifth (highest)1.14 (1.10-1.18)1.06 (1.00-1.12)0.98 (0.91-1.05)1.18 (1.08-1.30)1.15 (1.07-1.23)
          Ethnic concentration quintile
              First (lowest)1.02 (0.92-1.12)1.21 (1.04-1.41)1.08 (0.93-1.24)1.16 (0.91-1.49)1.07 (0.87-1.32)
              Second1.01 (0.94-1.09)1.16 (1.03-1.32)1.09 (0.98-1.22)0.92 (0.76-1.12)1.07 (0.93-1.24)
              Third1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]
              Fourth0.91 (0.87-0.96)0.96 (0.88-1.05)0.87 (0.81-0.95)1.07 (0.94-1.23)0.89 (0.8-0.99)
              Fifth (highest)0.82 (0.78-0.86)0.76 (0.70-0.82)0.77 (0.72-0.83)0.88 (0.77-0.99)0.81 (0.74-0.89)
          Material deprivation quintile
              First (lowest)1.06 (1.02-1.09)0.99 (0.94-1.05)1.11 (1.05-1.18)0.97 (0.89-1.05)1.13 (1.06-1.19)
              Second1.00 (0.97-1.03)1.01 (0.96-1.07)1.01 (0.95-1.07)0.98 (0.91-1.06)1.03 (0.98-1.08)
              Third1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]
              Fourth0.89 (0.86-0.92)0.89 (0.84-0.94)0.93 (0.87-0.98)0.77 (0.70-0.85)0.94 (0.89-0.99)
              Fifth (highest)0.77 (0.74-0.81)0.86 (0.80-0.93)0.93 (0.86-0.99)0.76 (0.68-0.86)0.86 (0.80-0.92)
          CharacteristicAdjusted prevalence ratio (95% confidence interval)*
          IndiaChinaPhilippinesPakistanSri Lanka
          Education
              University degree or higher1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]
              Some university0.91 (0.86-0.96)0.87 (0.8-0.93)0.84 (0.79-0.91)1.28 (1.11-1.48)0.88 (0.79-0.98)
          Nonuniversity qualifications (e.g., college diploma)0.81 (0.78-0.83)0.55 (0.52-0.58)0.82 (0.77-0.86)0.90 (0.84-0.97)0.70 (0.66-0.74)
              Secondary or less0.96 (0.93-0.99)0.75 (0.71-0.79)0.78 (0.74-0.82)0.91 (0.84-1.00)0.89 (0.83-0.95)
              None0.71 (0.67-0.75)0.58 (0.52-0.65)0.76 (0.69-0.84)0.92 (0.81-1.05)0.72 (0.66-0.79)
          Time since arrival in Canada, yr
              ≥ 201.41 (1.32-1.51)1.78 (1.54-2.06)1.77 (1.61-1.95)2.04 (1.63-2.55)1.48 (1.32-1.67)
              15-192.09 (1.96-2.23)3.57 (3.14-4.06)2.35 (2.15-2.57)2.52 (2.05-3.09)1.83 (1.64-2.06)
              10-141.97 (1.85-2.09)2.92 (2.58-3.31)2.17 (1.99-2.37)2.04 (1.67-2.50)1.87 (1.67-2.10)
              4-91.22 (1.15-1.30)1.37 (1.21-1.55)1.51 (1.39-1.65)1.23 (1.01-1.51)1.19 (1.06-1.33)
              < 41.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]
          Language ability
              English1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]
              French0.71 (0.69-0.73)0.73 (0.70-0.75)0.93 (0.88-0.98)0.60 (0.56-0.65)0.77 (0.74-0.81)
              Both1.16 (1.04-1.29)0.93 (0.75-1.17)1.60 (1.12-2.28)1.18 (0.86-1.63)1.02 (0.78-1.34)
              Neither0.71 (0.69-0.73)0.73 (0.70-0.75)0.93 (0.88-0.98)0.60 (0.56-0.65)0.77 (0.74-0.81)
          Marital status
              Married1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]
              Separated, divorced,
              widowed
          1.09 (1.01-1.18)1.23 (1.11-1.37)1.08 (0.96-1.21)1.10 (0.90-1.34)0.98 (0.88-1.10)
              Single1.12 (1.09-1.15)1.19 (1.14-1.25)0.97 (0.93-1.01)1.24 (1.16-1.33)1.05 (1.01-1.10)
          Immigrant class
              Economic1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]1.00 [Reference]
              Family0.80 (0.78-0.82)0.86 (0.82-0.91)0.84 (0.81-0.88)0.82 (0.76-0.88)0.73 (0.69-0.77)
              Refugee0.96 (0.89-1.04)0.73 (0.67-0.80)1.33 (0.98-1.79)1.39 (1.28-1.51)0.83 (0.79-0.87)
              Other1.04 (0.93-1.17)0.68 (0.60-0.76)1.06 (0.90-1.25)1.33 (1.10-1.62)0.95 (0.86-1.05)

          *Adjusted for world region of birth, sex, residence, age category, neighbourhood income quintile, material deprivation quintile, ethnic concentration quintile, education, time since arrival in Canada, language ability, marital status and immigrant class.

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          CMAJ Open: 4 (4)
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          13 Dec 2016
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          Registration for deceased organ and tissue donation among Ontario immigrants: a population-based cross-sectional study
          Alvin Ho-ting Li, Ngan N. Lam, Sonny Dhanani, Matthew Weir, Versha Prakash, Joseph Kim, Greg Knoll, Amit X. Garg
          Oct 2016, 4 (4) E551-E561; DOI: 10.9778/cmajo.20160024

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          Registration for deceased organ and tissue donation among Ontario immigrants: a population-based cross-sectional study
          Alvin Ho-ting Li, Ngan N. Lam, Sonny Dhanani, Matthew Weir, Versha Prakash, Joseph Kim, Greg Knoll, Amit X. Garg
          Oct 2016, 4 (4) E551-E561; DOI: 10.9778/cmajo.20160024
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