Dose response of sodium glucose cotransporter-2 inhibitors in relation to urinary tract infections: a systematic review and network meta-analysis of randomized …

JR Donnan, CA Grandy, E Chibrikov… - … Open Access Journal, 2018 - cmajopen.ca
Background: The sodium glucose cotransporter-2 (SGLT2) inhibitors are a novel group of
drugs for treatment of type 2 diabetes mellitus. We investigated whether there is a dose …

SGLT2 inhibitors and urinary tract infections

J Wilding - Nature Reviews Endocrinology, 2019 - nature.com
Sodium–glucose cotransporter 2 (SGLT2) inhibitors are a fairly new class of treatment for
diabetes mellitus. Some data suggest SGLT2 inhibitors are associated with a risk of severe …

Effects of SGLT2 inhibitors on UTIs and genital infections in type 2 diabetes mellitus: a systematic review and meta-analysis

J Liu, L Li, S Li, P Jia, K Deng, W Chen, X Sun - Scientific reports, 2017 - nature.com
Previous trial evidence suggested potential risk of serious urinary tract infections (UTIs) and
genital infections in type 2 diabetes patients using sodium glucose co-transporter-2 …

SGLT-2 inhibitors and the risk of infections: a systematic review and meta-analysis of randomized controlled trials

R Puckrin, MP Saltiel, P Reynier, L Azoulay, OHY Yu… - Acta …, 2018 - Springer
Aims There is concern about the infection-related safety profile of sodium–glucose co-
transporter 2 (SGLT-2) inhibitors. We aimed to determine the effect of SGLT-2 inhibitors on …

Sodium-Glucose Cotransporter 2 Inhibitors and Urinary Tract Infection: Is There Room for Real Concern?

N Wiegley, PN So - Kidney360, 2022 - journals.lww.com
Abstract Sodium-glucose cotransporter 2 (SGLT2) inhibitors have revolutionized our
armamentarium for kidney and heart protection in patients with or without diabetes. Based …

[HTML][HTML] Use of sodium-glucose cotransporter-2 inhibitors and urinary tract infections in type 2 diabetes patients: a systematic review

IR Figueiredo, SCP Rose, NB Freire… - Revista da Associação …, 2019 - SciELO Brasil
SUMMARY Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are drugs that act by
maintaining glycosuria. Recent studies have shown promising effects of these in the …

Urinary tract and genital infections in patients with type 2 diabetes treated with sodium‐glucose co‐transporter 2 inhibitors: a meta‐analysis of randomized controlled …

D Li, T Wang, S Shen, Z Fang, Y Dong… - Diabetes, Obesity and …, 2017 - Wiley Online Library
Aims To evaluate the effects of different sodium‐glucose co‐transporter 2 (SGLT2) inhibitors
on the risk of urinary tract infections (UTIs) and genital infections in patients with type 2 …

The risk for urinary tract infections with sodium-glucose cotransporter 2 inhibitors: no longer a cause of concern?

PA Sarafidis, A Ortiz - Clinical Kidney Journal, 2020 - academic.oup.com
Abstract Sodium–glucose co-transporter-2 (SGLT2) inhibitors improve cardiovascular and
renal outcomes in patients with type 2 diabetes, including those with diabetic kidney …

[HTML][HTML] Sodium-Glucose Cotransporter-2 Inhibitors and Urinary Tract Infections: A Propensity Score–matched Population-based Cohort Study

W Alkabbani, A Zongo, JK Minhas-Sandhu… - Canadian Journal of …, 2022 - Elsevier
Abstract Objectives Sodium-glucose cotransporter-2 (SGLT2) inhibitor–induced glycosuria is
hypothesized to increase the risk of urinary tract infections (UTIs). We assessed the risk of …

[HTML][HTML] Sodium-glucose cotransporter-2 inhibitors increase urinary tract infections?—a cross sectional analysis of a nationwide Japanese claims database

G Anan, D Kikuchi, K Omae, T Hirose, K Okada… - Endocrine …, 2023 - jstage.jst.go.jp
Abstract Sodium-glucose cotransporter-2 (SGLT2) inhibitors are a novel class of antidiabetic
drugs. Guidelines for the proper use of SGLT2 inhibitors recommend caution regarding …