Prescribed targets for titration of vasopressors in septic shock: a retrospective cohort study

C St-Arnaud, JF Éthier, C Hamielec… - … Open Access Journal, 2013 - cmajopen.ca
Background Without robust clinical evidence to guide titration of vasopressors in septic
shock, it is unclear how dosing of these potent medications occurs. We sought to measure …

Vasopressor administration and sepsis: a survey of Canadian intensivists

F Lamontagne, DJ Cook, NKJ Adhikari, M Briel… - Journal of critical …, 2011 - Elsevier
INTRODUCTION: Patients with septic shock often receive intravenous vasopressor
infusions, with little evidence available to guide their titration. We surveyed Canadian …

[HTML][HTML] Current use of vasopressors in septic shock

TWL Scheeren, J Bakker, D De Backer, D Annane… - Annals of intensive …, 2019 - Springer
Background Vasopressors are commonly applied to restore and maintain blood pressure in
patients with sepsis. We aimed to evaluate the current practice and therapeutic goals …

Blood pressure targets for vasopressor therapy: a systematic review

F D'Aragon, EP Belley-Cote, MO Meade, F Lauzier… - Shock, 2015 - journals.lww.com
Physicians often prescribe vasopressors to correct pathological vasodilation and improve
tissue perfusion in patients with septic shock, but the evidence to inform practice on …

Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock

F Lamontagne, AG Day, MO Meade, DJ Cook… - Intensive care …, 2018 - Springer
Purpose Guidelines for shock recommend mean arterial pressure (MAP) targets for
vasopressor therapy of at least 65 mmHg and, until recently, suggested that patients with …

[HTML][HTML] Should we initiate vasopressors earlier in patients with septic shock: A mini systemic review

HX Zhou, CF Yang, HY Wang, Y Teng… - World Journal of Critical …, 2023 - ncbi.nlm.nih.gov
Septic shock treatment remains a major challenge for intensive care units, despite the recent
prominent advances in both management and outcomes. Vasopressors serve as a …

Mortality, morbidity, and costs after implementation of a vasopressin guideline in medical intensive care patients with septic shock: an interrupted time series analysis

SR Bauer, GL Sacha, AJ Reddy - Annals of …, 2020 - journals.sagepub.com
Background: Vasopressin decreases vasopressor requirements in patients with septic
shock. However, the optimal norepinephrine dose for initiation or cessation of vasopressin is …

[HTML][HTML] Vasopressor use for severe hypotension—a multicentre prospective observational study

F Lamontagne, DJ Cook, MO Meade, A Seely… - PLoS …, 2017 - journals.plos.org
Background The optimal approach to titrate vasopressor therapy is unclear. Recent sepsis
guidelines recommend a mean arterial pressure (MAP) target of 65 mmHg and higher for …

Evaluation of vasopressor exposure and mortality in patients with septic shock

RJ Roberts, TA Miano, DA Hammond… - Critical care …, 2020 - journals.lww.com
Objectives: The objectives of this study were to: 1) determine the association between
vasopressor dosing intensity during the first 6 hours and first 24 hours after the onset of …

Efficacy and outcomes after vasopressin guideline implementation in septic shock

JY Wu, JL Stollings, AP Wheeler… - Annals of …, 2017 - journals.sagepub.com
Background: In septic shock, the dose of norepinephrine (NE) at which vasopressin (AVP)
should be added is unknown. Following an increase in AVP price, our medical intensive …