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Frostbite is an injury that occurs when the skin and tissues are exposed to temperatures
below their freezing point. This type of injury can lead to various complications such as …

We performed a scoping review to identify the extent of the literature describing the use of
iloprost in the treatment of frostbite. Iloprost is a stable synthetic analog of prostaglandin I2 …

Abstract This Clinical Practice Guideline addresses severe frostbite treatment. We defined
severe frostbite as atmospheric cooling that results in a perfusion deficit to the extremities …

Introduction: Freezing cold injuries (FCI) are a common risk in extreme cold weather warfare
operations. The Norwegian Armed Forces (NAF) have the expertise and capabilities in …

Background Frostbite is a severe thermal injury, which characterized by tissue necrosis with
a high percentage of amputations, disability of patients. Methods According to the databases …

Frostbite is caused by exposure to cold temperatures and can lead to severe injury resulting
in amputations. Tissue plasminogen activator (tPA) is a thrombolytic agent that has …

Introduction Our objective was to perform a systematic review of the outcomes of various
frostbite treatments to determine which treatments are effective. We also planned to perform …

ABSTRACT Introduction: Cold Weather Injury (CWI) represents a spectrum of pathology, the
two main divisions being Freezing Cold Injury (FCI) and Non-Freezing Cold Injury (NFCI) …

Purpose We assessed the effectiveness and safety of a 5-day intravenous prostaglandin
(iloprost) protocol at reducing digital amputation for patients with severe frostbite injuries at …