Are take‐home naloxone programmes effective? Systematic review utilizing application of the Bradford Hill criteria

R McDonald, J Strang - Addiction, 2016 - Wiley Online Library
Abstract Background and Aims Fatal outcome of opioid overdose, once detected, is
preventable through timely administration of the antidote naloxone. Take‐home naloxone …

Naloxone dosage for opioid reversal: current evidence and clinical implications

R Rzasa Lynn, JL Galinkin - Therapeutic advances in drug …, 2018 - journals.sagepub.com
Opioid-related mortality is a growing problem in the United States, and in 2015 there were
over 33,000 opioid-related deaths. To combat this mortality trend, naloxone is increasingly …

A review of opioid overdose prevention and naloxone prescribing: implications for translating community programming into clinical practice

SR Mueller, AY Walley, SL Calcaterra… - Substance …, 2015 - journals.sagepub.com
Background As physicians have increased opioid prescribing, overdose deaths from
pharmaceutical opioids have substantially increased in the United States. Naloxone …

Naloxone for heroin, prescription opioid, and illicitly made fentanyl overdoses: challenges and innovations responding to a dynamic epidemic

N Fairbairn, PO Coffin, AY Walley - International Journal of Drug Policy, 2017 - Elsevier
Community-based overdose prevention programs first emerged in the 1990's and are now
the leading public health intervention for overdose. Key elements of these programs are …

[HTML][HTML] Distribution of take-home opioid antagonist kits during a synthetic opioid epidemic in British Columbia, Canada: a modelling study

MA Irvine, JA Buxton, M Otterstatter… - The Lancet Public …, 2018 - thelancet.com
Background Illicit use of high-potency synthetic opioids has become a global issue over the
past decade. This misuse is particularly pronounced in British Columbia, Canada, where a …

[HTML][HTML] Known fentanyl use among clients of harm reduction sites in British Columbia, Canada

M Karamouzian, K Papamihali, B Graham… - International Journal of …, 2020 - Elsevier
Abstract Background North America is in the midst of an opioid overdose epidemic and it is
commonly suggested that exposure to fentanyl is unknown. Using a provincial survey of …

[HTML][HTML] How do naloxone-based interventions work to reduce overdose deaths: a realist review

NM Miller, B Waterhouse-Bradley, C Campbell… - Harm reduction …, 2022 - Springer
Background Naloxone-based interventions as part of health systems can reverse an opioid
overdose. Previous systematic reviews have identified the effectiveness of naloxone; …

[HTML][HTML] Addressing intersecting housing and overdose crises in Vancouver, Canada: opportunities and challenges from a tenant-led overdose response intervention …

G Bardwell, T Fleming, AB Collins, J Boyd… - Journal of urban …, 2019 - Springer
We examined the acceptability, feasibility, and implementation of the Tenant Overdose
Response Organizers program (TORO)—a tenant-led naloxone training and distribution …

[HTML][HTML] “It's an emotional roller coaster… But sometimes it's fucking awesome”: meaning and motivation of work for peers in overdose response environments in …

BB Pauly, Z Mamdani, L Mesley, S McKenzie… - International Journal of …, 2021 - Elsevier
Abstract Background The province of British Columbia (BC), Canada is amid dual public
health emergencies in which the overdose epidemic declared in 2016 has been …

Characterizing peer roles in an overdose crisis: Preferences for peer workers in overdose response programs in emergency shelters

G Bardwell, T Kerr, J Boyd, R McNeil - Drug and alcohol dependence, 2018 - Elsevier
Objectives A growing body of research points to increasing peer involvement in programs for
people who use drugs, although this work has focused primarily on naloxone education and …