Colchicine poisoning: the dark side of an ancient drug

Y Finkelstein, SE Aks, JR Hutson, DN Juurlink… - Clinical …, 2010 - Taylor & Francis
Introduction. Colchicine is used mainly for the treatment and prevention of gout and for familial
Mediterranean fever (FMF). It has a narrow therapeutic index, with no clear-cut distinction …

Overdose risk in young children of women prescribed opioids

Y Finkelstein, EM Macdonald, A Gonzalez… - …, 2017 - publications.aap.org
METHODS: We conducted a population-based, nested case control study in Ontario,
Canada, between 2002 and 2015. We identified children aged≤ 10 years, whose mothers …

[HTML][HTML] Multicenter trial of a combination probiotic for children with gastroenteritis

…, K Hurley, PM Sherman, Y Finkelstein… - … England Journal of …, 2018 - Mass Medical Soc
Background Gastroenteritis accounts for approximately 1.7 million visits to the emergency
department (ED) by children in the United States every year. Data to determine whether the …

[HTML][HTML] Interventions for adolescent substance abuse: An overview of systematic reviews

JK Das, RA Salam, A Arshad, Y Finkelstein… - Journal of Adolescent …, 2016 - Elsevier
Many unhealthy behaviors often begin during adolescence and represent major public
health challenges. Substance abuse has a major impact on individuals, families, and …

Colchicine for prevention of postpericardiotomy syndrome and postoperative atrial fibrillation: the COPPS-2 randomized clinical trial

…, D Cugola, D Cumetti, O Dyrda, S Ferrua, Y Finkelstein… - Jama, 2014 - jamanetwork.com
Importance Postpericardiotomy syndrome, postoperative atrial fibrillation (AF), and
postoperative effusions may be responsible for increased morbidity and health care costs after …

[HTML][HTML] Comparative safety of anti-epileptic drugs during pregnancy: a systematic review and network meta-analysis of congenital malformations and prenatal …

AA Veroniki, E Cogo, P Rios, SE Straus, Y Finkelstein… - BMC medicine, 2017 - Springer
Background Pregnant women with epilepsy frequently experience seizures related to
pregnancy complications and are often prescribed anti-epileptic drugs (AEDs) to manage their …

Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network …

AA Veroniki, P Rios, E Cogo, SE Straus, Y Finkelstein… - BMJ open, 2017 - bmjopen.bmj.com
Objectives Compare the safety of antiepileptic drugs (AEDs) on neurodevelopment of infants/children
exposed in utero or during breast feeding. Design and setting Systematic review …

Post–COVID-19 conditions among children 90 days after SARS-CoV-2 infection

…, DJ Tancredi, J Xie, K Kim, Y Finkelstein… - JAMA Network …, 2022 - jamanetwork.com
Importance Little is known about the risk factors for, and the risk of, developing post–COVID-19
conditions (PCCs) among children. Objectives To estimate the proportion of SARS-CoV-2…

Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome

…, LM Pereira, Y Finkelstein… - Proceedings of the …, 2014 - National Acad Sciences
Rett syndrome (RTT) is a severe X-linked neurodevelopmental disorder mainly affecting
females and is associated with mutations in MECP2, the gene encoding methyl CpG-binding …

Recurrence and outcomes of Stevens-Johnson syndrome and toxic epidermal necrolysis in children

Y Finkelstein, GS Soon, P Acuna, M George… - …, 2011 - publications.aap.org
OBJECTIVES: To report clinical course, etiology, management, and long-term outcomes of
children suffering from Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN). …