Importance Little is known about the relationship between perioperative high-sensitivity
troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac …

Objective: Postextubation distress after a successful spontaneous breathing trial is associated
with increased morbidity and mortality. Predicting postextubation distress is therefore a …

Background The effect on cardiovascular outcomes of withholding angiotensin-converting
enzyme inhibitors or angiotensin II receptor blockers in chronic users before noncardiac …

BACKGROUND: Among adults undergoing contemporary noncardiac surgery, little is
known about the frequency and timing of death and the associations between perioperative …

… Le Manach and Landais had full access to all the data in the study and took responsibility for
… Le Manach, Collins, and Landais in analysis and interpretation of data; Drs. Le Manach and …

Importance Patients undergoing surgery for a hip fracture have a higher risk of mortality and
major complications compared with patients undergoing an elective total hip replacement (…

Background There is substantial variability in the perioperative administration of aspirin in
patients undergoing noncardiac surgery, both among patients who are already on an aspirin …

Background Respiratory arterial pulse pressure variations (PPV) are the best predictors of
fluid responsiveness in mechanically ventilated patients during general anesthesia. However, …

Background Tight perioperative control of blood glucose improves the outcome of diabetic
patients undergoing cardiac surgery. Because stress response and cardiopulmonary bypass …

Background There is a need to increase access to surgical treatments in African countries,
but perioperative complications represent a major global health-care burden. There are few …