Calcium channel density and hippocampal cell death with age in long-term culture
NM Porter, O Thibault, V Thibault, KC Chen… - Journal of …, 1997 - Soc Neuroscience
The expression of voltage-gated calcium (Ca 2+ ) channel activity in brain cells is known to
be important for several aspects of neuronal development. In addition, excessive Ca 2+ influx …
be important for several aspects of neuronal development. In addition, excessive Ca 2+ influx …
Factors that could explain the increasing prevalence of type 2 diabetes among adults in a Canadian province: a critical review and analysis
V Thibault, M Bélanger, E LeBlanc, L Babin… - Diabetology & metabolic …, 2016 - Springer
Background The prevalence of diabetes has increased since the last decade in New Brunswick.
Identifying factors contributing to the increase in diabetes prevalence will help inform an …
Identifying factors contributing to the increase in diabetes prevalence will help inform an …
Vitamin D hormone confers neuroprotection in parallel with downregulation of L-type calcium channel expression in hippocampal neurons
LD Brewer, V Thibault, KC Chen… - Journal of …, 2001 - Soc Neuroscience
Although vitamin D hormone (VDH; 1,25-dihydroxyvitamin D 3 ), the active metabolite of
vitamin D, is the major Ca 2+ -regulatory steroid hormone in the periphery, it is not known …
vitamin D, is the major Ca 2+ -regulatory steroid hormone in the periphery, it is not known …
Body image self-conscious emotions get worse throughout adolescence and relate to physical activity behavior in girls and boys
Body image is a commonly-reported factor perpetuating declines in physical activity levels
during adolescence. However, the evidence is predominantly qualitative, cross-sectional, and …
during adolescence. However, the evidence is predominantly qualitative, cross-sectional, and …
Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models
…, I Kadish, EM Blalock, KC Chen, V Thibault… - Journal of …, 2005 - Soc Neuroscience
Astrocyte reactivity (ie, activation) and associated neuroinflammation are increasingly
thought to contribute to neurodegenerative disease. However, the mechanisms that trigger …
thought to contribute to neurodegenerative disease. However, the mechanisms that trigger …
Physical activity motives have a direct effect on mental health
I Doré, V Thibault, MP Sylvestre… - … Journal of Medicine …, 2022 - Wiley Online Library
Physical activity (PA) motives are associated with both moderate‐to‐vigorous intensity PA (MVPA)
and mental health. Studies examining whether PA motives relate directly to mental …
and mental health. Studies examining whether PA motives relate directly to mental …
One size does not fit all: identifying clusters of physical activity, screen time, and sleep behaviour co-development from childhood to adolescence
Purpose Canada was the first to adopt comprehensive 24-h movement guidelines that include
recommendations for physical activity, screen time and sleep to promote health benefits. …
recommendations for physical activity, screen time and sleep to promote health benefits. …
Influence of a pay-for-performance program on glycemic control in patients living with diabetes by family physicians in a Canadian province
E LeBlanc, M Bélanger, V Thibault, L Babin… - Canadian journal of …, 2017 - Elsevier
Objectives We evaluated the influence of the introduction of a pay-for-performance program
implemented in 2010 for family physicians on the glycemic control of patients with diabetes. …
implemented in 2010 for family physicians on the glycemic control of patients with diabetes. …
Increased vulnerability of hippocampal neurons with age in culture: temporal association with increases in NMDA receptor current, NR2A subunit expression and …
LD Brewer, O Thibault, J Staton, V Thibault, JT Rogers… - Brain research, 2007 - Elsevier
Excessive glutamate (Glu) stimulation of the NMDA-R is a widely recognized trigger for Ca 2+
-mediated excitotoxicity. Primary neurons typically show a large increase in vulnerability to …
-mediated excitotoxicity. Primary neurons typically show a large increase in vulnerability to …
Puberty timing and relative age as predictors of physical activity discontinuation during adolescence
Among same-age adolescents, those who enter puberty relatively later and those who are
relatively younger (eg, born later in the year) might be at greater risk of physical activity …
relatively younger (eg, born later in the year) might be at greater risk of physical activity …