Scoping reviews, a type of knowledge synthesis, follow a systematic approach to map evidence
on a topic and identify main concepts, theories, sources, and knowledge gaps. Although …

Background Serious infections are a major concern for patients considering treatments for
rheumatoid arthritis. Evidence is inconsistent as to whether biological drugs are associated …

Importance Systematic reviews of diagnostic test accuracy synthesize data from primary
diagnostic studies that have evaluated the accuracy of 1 or more index tests against a reference …

Objective To summarise and compare the efficacy and safety of various oral anticoagulants (dabigatran,
rivaroxaban, apixaban, and vitamin K antagonists) and antiplatelet agents (…

Background The use of network meta-analysis has increased dramatically in recent years.
WinBUGS, a freely available Bayesian software package, has been the most widely used …

Background Rapid reviews are an accelerated evidence synthesis approach intended to
meet the timely needs of decision-makers in healthcare settings. Quality of conduct and …

Background There has been increasing concern regarding the potential effects of the
commercialization of research. Methods In order to examine the relationships between funding …

Objectives: The English language is generally perceived to be the universal language of
science. However, the exclusive reliance on English-language studies may not represent all of …

Background Although triptans are widely used in the acute management of migraine, there
is uncertainty around the comparative efficacy of triptans among each other and vs non‐…

Importance Many anticoagulant strategies are available for the treatment of acute venous
thromboembolism, yet little guidance exists regarding which drug is most effective and safe. …