Ablation of P/Q-type Ca2+ channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the α1A-subunit

…, DB Wheeler, SB Lee, TG Lee… - Proceedings of the …, 1999 - National Acad Sciences
The Ca 2+ channel α 1A -subunit is a voltage-gated, pore-forming membrane protein positioned
at the intersection of two important lines of research: one exploring the diversity of Ca 2+ …

[HTML][HTML] Lack of the burst firing of thalamocortical relay neurons and resistance to absence seizures in mice lacking α1G T-type Ca2+ channels

D Kim, I Song, S Keum, T Lee, MJ Jeong, SS Kim… - Neuron, 2001 - cell.com
T-type Ca 2+ currents have been proposed to be involved in the genesis of spike-and-wave
discharges, a sign of absence seizures, but direct evidence in vivo to support this hypothesis …

Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox

…, G Cheng, R Shapira, JM Kinkade, T Lee… - The Journal of cell …, 2001 - rupress.org
High molecular weight homologues of gp91phox, the superoxide-generating subunit of
phagocyte nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase, have been …

Novel compound 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) prevents 2, 3, 7, 8-TCDD-induced toxicity by …

…, DK Kim, YH Kim, KJ Shin, MS Han, TG Lee… - Molecular …, 2006 - ASPET
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a widespread environmental pollutant with
many toxic effects, including endocrine disruption, reproductive dysfunction, immunotoxicity, …

Proteomic analysis of tumor necrosis factor-α-induced secretome of human adipose tissue-derived mesenchymal stem cells

MJ Lee, J Kim, MY Kim, YS Bae, SH Ryu… - Journal of proteome …, 2010 - ACS Publications
Human adipose tissue-derived mesenchymal stem cells (hASCs) are useful for regeneration
of inflamed or injured tissues. To identify secreted hASC proteins during inflammation, …

[HTML][HTML] Regulation of the neutrophil respiratory burst oxidase: identification of an activation domain in p67phox

CH Han, JLR Freeman, T Lee, SA Motalebi… - Journal of Biological …, 1998 - ASBMB
Superoxide generation by the neutrophil respiratory burst oxidase (NADPH oxidase) can be
reconstituted in a cell-free system using flavocytochrome b 558 and the cytosolic proteins …

Supramolecular fishing for plasma membrane proteins using an ultrastable synthetic host–guest binding pair

DW Lee, KM Park, M Banerjee, SH Ha, T Lee, K Suh… - Nature …, 2011 - nature.com
Membrane proteomics, the large-scale global analysis of membrane proteins, is often constrained
by the efficiency of separating and extracting membrane proteins. Recent approaches …

Altered nociceptive response in mice deficient in the α1B subunit of the voltage-dependent calcium channel

C Kim, K Jun, T Lee, SS Kim, MW McEnery… - Molecular and Cellular …, 2001 - Elsevier
Calcium influx through N-type calcium channels mediates synaptic transmission at
numerous central synapses and transduces nociceptive information in the spinal dorsal horn. …

Identification of a compound that directly stimulates phospholipase C activity

YS Bae, TG Lee, JC Park, JH Hur, Y Kim, K Heo… - Molecular …, 2003 - ASPET
Phosphoinositide-specific phospholipase C (PLC) plays a pivotal role in the signal
transduction of various cellular responses. However, although it is undeniably important that …

[HTML][HTML] Lysophosphatidylcholine activates adipocyte glucose uptake and lowers blood glucose levels in murine models of diabetes

…, BD Lee, HJ Lee, SJ Lee, JI Kim, TG Lee… - Journal of Biological …, 2009 - ASBMB
Glucose homeostasis is maintained by the orchestration of peripheral glucose utilization
and hepatic glucose production, mainly by insulin. In this study, we found by utilizing a …