User profiles for Steven Yip

Steve Kim Fung Yip

Head of Reference and Research Services, Library, Hong Kong University of Science and …
Verified email at ust.hk
Cited by 147

[HTML][HTML] ATM-deficient cancers provide new opportunities for precision oncology

…, M Kumar, S Radhamani, G Arthur, S Goutam, S Yip… - Cancers, 2020 - mdpi.com
Poly-ADP ribose polymerase (PARP) inhibitors are currently used in the treatment of several
cancers carrying mutations in the breast and ovarian cancer susceptibility genes BRCA1 …

BRCA2, ATM, and CDK12 Defects Differentially Shape Prostate Tumor Driver Genomics and Clinical Aggression

E Warner, C Herberts, S Fu, S Yip, A Wong… - Clinical Cancer …, 2021 - AACR
Purpose: DNA damage repair (DDR) defects are common across cancer types and can indicate
therapeutic vulnerability. Optimal exploitation of DDR defects in prostate cancer requires …

Clinical outcomes in cyclin-dependent kinase 12 mutant advanced prostate cancer

MA Reimers, SM Yip, L Zhang, M Cieslik, M Dhawan… - European urology, 2020 - Elsevier
Background Cyclin-dependent kinase 12 (CDK12) loss occurs in 3–7% of metastatic prostate
cancer patients and is characterized by a genomic instability signature, but the clinical …

Activating AKT1 and PIK3CA mutations in metastatic castration-resistant prostate cancer

…, G Wang, E Schönlau, H Xue, D Lin, A Gleave, S Yip… - European urology, 2020 - Elsevier
Background Activating mutations in AKT1 and PIK3CA are undercharacterised in metastatic
castration-resistant prostate cancer (mCRPC), but are linked to activation of …

Activity of platinum-based chemotherapy in patients with advanced prostate cancer with and without DNA repair gene aberrations

…, O Sartor, E Ledet, G Di Lorenzo, SM Yip… - JAMA network …, 2020 - jamanetwork.com
Importance DNA repair gene aberrations occur in 20% to 30% of patients with castration-resistant
prostate cancer (CRPC), and some of these aberrations have been associated with …

Checkpoint inhibitors in patients with metastatic renal cell carcinoma: results from the international metastatic renal cell carcinoma database consortium

SM Yip, C Wells, R Moreira, A Wong, S Srinivas… - Cancer, 2018 - Wiley Online Library
BACKGROUND To the authors' knowledge, outcomes and prognostic tools have yet to be
clearly defined in patients with metastatic renal cell carcinoma (mRCC) who are treated with …

Estimation of the basic reproduction number of enterovirus 71 and coxsackievirus A16 in hand, foot, and mouth disease outbreaks

E Ma, C Fung, SHL Yip, C Wong… - The Pediatric …, 2011 - journals.lww.com
Background: Coxsackievirus A16 (Cox A16) and enterovirus 71 (EV71) are common pathogens
causing hand, foot, and mouth disease (HFMD) in pediatric population. Little is known …

Cell-free DNA modification dynamics in abiraterone acetate-treated prostate cancer patients

J Gordevičius, A Kriščiūnas, DE Groot, SM Yip… - Clinical Cancer …, 2018 - AACR
Purpose: Primary resistance to abiraterone acetate (AA), a key medication for the treatment
of metastatic castration-resistant prostate cancer, occurs in 20% to 40% of patients. We aim …

Changing roles of reference librarians: the case of the HKUST institutional repository

DLH Chan, CSY Kwok, SKF Yip - Reference services review, 2005 - emerald.com
Purpose – This paper proposes describing how reference librarians in an academic library
recruit content for its institutional repository, and how their roles have been changed in the …

DNA repair defects in prostate cancer: impact for screening, prognostication and treatment

EW Warner, SM Yip, KN Chi, AW Wyatt - BJU international, 2019 - Wiley Online Library
Failure of effective DNA damage repair is a hallmark of cancer, but was previously
underappreciated as a driver of aggressive prostate cancer. However, recent international …