Mice that overexpress the human mutant amyloid precursor protein (hAPP) show learning
deficits, but the apparent lack of a relationship between these deficits and the progressive β-…

Importance Approximately one-third of children experiencing acute concussion experience
ongoing somatic, cognitive, and psychological or behavioral symptoms, referred to as …

The aspartyl protease β-site amyloid precursor protein cleaving enzyme 1 (BACE1) initiates
processing of amyloid precursor protein (APP) into amyloid β (Aβ) peptide, the major …

Background Vomiting limits the success of oral rehydration in children with gastroenteritis. We
conducted a double-blind trial to determine whether a single oral dose of ondansetron, an …

Importance Although concussion treatment guidelines advocate rest in the immediate postinjury
period until symptoms resolve, no clear evidence has determined that avoiding physical …

Binding of dopamine receptor ligands to human D2 and D3 receptors was characterized in
Chinese hamster ovary (CHO) cells using the dopamine D2 receptor antagonist [125I] …

Importance Little is known about the risk factors for, and the risk of, developing post–COVID-19
conditions (PCCs) among children. Objectives To estimate the proportion of SARS-CoV-2…

OBJECTIVE. The goal was to determine, in children with myocarditis, the frequency of various
presenting symptoms and the sensitivity of clinical and laboratory investigations routinely …

Background Acute gastroenteritis develops in millions of children in the United States every
year, and treatment with probiotics is common. However, data to support the use of …

Background Gastroenteritis accounts for approximately 1.7 million visits to the emergency
department (ED) by children in the United States every year. Data to determine whether the …