Since the publication of the Osteoporosis Canada guide-lines in 2002, there has been a
paradigm shift in the prevention and treatment of osteoporosis and fractures. 1, 2 The focus now …

Background Phosphate binders (calcium-based and calcium-free) are recommended to
lower serum phosphate and prevent hyperphosphataemia in patients with chronic kidney …

Osteoporosis is the most common cause of fragility fractures. Bone remodelling is essential
for repairing damaged areas within bone to preserve bone strength and for assisting in …

To determine whether type 2 diabetes is associated with fracture in older women, we
analyzed data from 9654 women, age 65 yr or older, in the Study of Osteoporotic Fractures. …

Background: Vertebral fractures are a hallmark of postmenopausal osteoporosis and an
important end point in trials of osteoporosis treatment, but the clinical significance of these …

Background: The study objectives were to determine fracture rates in relation to bone mineral
density at various central skeletal sites, using the World Health Organization definition for …

The incidences of osteoporosis and chronic kidney disease (CKD) both increase with
increasing age, yet there is a paucity of data on treatments for osteoporosis in the setting of …

To determine if alendronate had differential effects on BMD and fracture by renal function,
we performed a secondary data analysis of women participating in the FIT. Alendronate …

Background An increased rate of hip fractures has been reported in patients with end-stage
renal disease, but the effect of less severe renal dysfunction on fracture risk is uncertain. …

OBJECTIVE—Compared with men and women without diabetes, individuals with type 2
diabetes have higher bone mineral density (BMD). However, they may still be at increased risk …