User profiles for Shelley L. McLeod

Shelley McLeod

Associate Professor, University of Toronto
Verified email at sinaihealth.ca
Cited by 4615

Drug treatments for covid-19: living systematic review and network meta-analysis

…, M Loeb, A Miroshnychenko, M Marcucci, SL McLeod… - bmj, 2020 - bmj.com
Objective To compare the effects of treatments for coronavirus disease 2019 (covid-19).
Design Living systematic review and network meta-analysis. Data sources WHO covid-19 …

[HTML][HTML] Defibrillation strategies for refractory ventricular fibrillation

…, IR Drennan, SL McLeod, L Turner… - … England Journal of …, 2022 - Mass Medical Soc
Background Despite advances in defibrillation technology, shock-refractory ventricular
fibrillation remains common during out-of-hospital cardiac arrest. Double sequential external …

[HTML][HTML] Federated learning for predicting clinical outcomes in patients with COVID-19

…, P Elnajjar, S Hickman, S Majumdar, SL McLeod… - Nature medicine, 2021 - nature.com
Federated learning (FL) is a method used for training artificial intelligence models with data
from multiple sources while maintaining data anonymity, thus removing many barriers to data …

Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets

…, D Brodie, KM Rowan, CL Hough, SL McLeod… - Intensive Care …, 2021 - Springer
Purpose Targeted temperature management (TTM) may improve survival and functional
outcome in comatose survivors of out-of-hospital cardiac arrest (OHCA), though the optimal …

Prophylaxis against covid-19: living systematic review and network meta-analysis

…, A Khamis, F Lamontagne, M Loeb, SL McLeod… - Bmj, 2021 - bmj.com
Updates This is the second version (first update) of the living systematic review, replacing the
previous version (available as a data supplement). When citing this paper please consider …

Improving access to automated external defibrillators in rural and remote settings: a drone delivery feasibility study

S Cheskes, SL McLeod, M Nolan… - Journal of the …, 2020 - Am Heart Assoc
Background Time to treatment is critical for survival from sudden cardiac arrest. Every
minute delay in defibrillation results in a 7% to 10% reduction in survival. This is particularly …

Transfusion of fresher vs older red blood cells in hospitalized patients: a systematic review and meta-analysis

…, NM Heddle, N Blumberg, SL McLeod… - Blood, The Journal …, 2016 - ashpublications.org
The impact of transfusing fresher vs older red blood cells (RBCs) on patient-important outcomes
remains controversial. Two recently published large trials have provided new evidence. …

Ketamine‐propofol versus propofol alone for procedural sedation in the emergency department: a systematic review and meta‐analysis

JW Yan, SL McLeod… - Academic Emergency …, 2015 - Wiley Online Library
Objectives Propofol is an agent commonly used for procedural sedation and analgesia (
PSA ) in the emergency department ( ED ), but it can cause respiratory depression and …

Prospective validation of the emergency heart failure mortality risk grade for acute heart failure: the ACUTE study

…, ML Edmonds, M Ivankovic, SL McLeod… - Circulation, 2019 - Am Heart Assoc
Background: Improved risk stratification of acute heart failure in the emergency department
may inform physicians’ decisions regarding patient admission or early discharge disposition. …

Remote Ischemic Perconditioning to Reduce Reperfusion Injury During Acute ST‐Segment–Elevation Myocardial Infarction: A Systematic Review and Meta‐Analysis

SL McLeod, A Iansavichene… - Journal of the American …, 2017 - Am Heart Assoc
Background Remote ischemic conditioning ( RIC ) is a noninvasive therapeutic strategy that
uses brief cycles of blood pressure cuff inflation and deflation to protect the myocardium …