User profiles for Scot E. Purdon
Scot PurdonClinical Professor, University of Alberta Verified email at ualberta.ca Cited by 5839 |
A meta-analysis of neuropsychological change to clozapine, olanzapine, quetiapine, and risperidone in schizophrenia
Cognitive impairment is a core feature of schizophrenia and a major impediment to social
and vocational rehabilitation. A number of studies have claimed cognitive benefits from …
and vocational rehabilitation. A number of studies have claimed cognitive benefits from …
Neuropsychological change in early phase schizophrenia during 12 months of treatment with olanzapine, risperidone, or haloperidol
SE Purdon, BDW Jones, E Stip, A Labelle… - Archives of general …, 2000 - jamanetwork.com
Background The purpose of this investigation was to test the efficacy of novel antipsychotic
medications in the treatment of cognitive impairment in early phase schizophrenia. Methods …
medications in the treatment of cognitive impairment in early phase schizophrenia. Methods …
Neuropsychological change in patients with schizophrenia after treatment with quetiapine or haloperidol.
SE Purdon, A Malla, A Labelle, W Lit - Journal of psychiatry and …, 2001 - ncbi.nlm.nih.gov
OBJECTIVE: To assess the efficacy of quetiapine, a recently introduced second generation
antipsychotic medication, in reducing cognitive impairment in patients with schizophrenia. …
antipsychotic medication, in reducing cognitive impairment in patients with schizophrenia. …
Compliance to health recommendations: A theoretical overview of message framing
Abstract Health care professionals have become increasingly interested in motivating
individuals to comply with health recommendations. One approach to this issue has been to …
individuals to comply with health recommendations. One approach to this issue has been to …
A meta-analysis of cognitive change with haloperidol in clinical trials of atypical antipsychotics: dose effects and comparison to practice effects
Prospective, double-blind, randomized trials comparing atypical antipsychotic drugs (APDs)
to typical APDs, such as haloperidol, indicate that atypical APDs provide a modest benefit to …
to typical APDs, such as haloperidol, indicate that atypical APDs provide a modest benefit to …
Association of age, antipsychotic medication, and symptom severity in schizophrenia with proton magnetic resonance spectroscopy brain glutamate level: a mega …
Importance Proton magnetic resonance spectroscopy (1H-MRS) studies indicate that altered
brain glutamatergic function may be associated with the pathophysiology of schizophrenia …
brain glutamatergic function may be associated with the pathophysiology of schizophrenia …
One-year double-blind study of the neurocognitive efficacy of olanzapine, risperidone, and haloperidol in schizophrenia
Neurocognitive deficits in schizophrenia can reach 1 to 2 standard deviations below healthy
controls. The comparative effect of typical and atypical antipsychotic medications on …
controls. The comparative effect of typical and atypical antipsychotic medications on …
Screening for cognitive dysfunction in unipolar depression: validation and evaluation of objective and subjective tools
Background Persistent cognitive dysfunction in unipolar depression (UD) contributes to
socio-occupational impairment, but there are no feasible methods to screen for and monitor …
socio-occupational impairment, but there are no feasible methods to screen for and monitor …
Optimising screening for cognitive dysfunction in bipolar disorder: validation and evaluation of objective and subjective tools
Introduction Cognitive impairment is common in bipolar disorder and contributes to socio-occupational
difficulties. The objective was to validate and evaluate instruments to screen for …
difficulties. The objective was to validate and evaluate instruments to screen for …
Spanish version of the Screen for Cognitive Impairment in Psychiatry (SCIP-S): Psychometric properties of a brief scale for cognitive evaluation in schizophrenia
OBJECTIVE: The Screen for Cognitive Impairment in Psychiatry (SCIP) is a brief scale
designed for detecting cognitive deficits in several psychotic and affective disorders. This study …
designed for detecting cognitive deficits in several psychotic and affective disorders. This study …