Background Antimicrobial resistance (AMR) poses a major threat to human health around
the world. Previous publications have estimated the effect of AMR on incidence, deaths, …

Background Sepsis is life-threatening organ dysfunction due to a dysregulated host response
to infection. It is considered a major cause of health loss, but data for the global burden of …

We previously piloted the concept of a Connectivity Map (CMap), whereby genes, drugs, and
disease states are connected by virtue of common gene-expression signatures. Here, we …

Importance The increasing burden due to cancer and other noncommunicable diseases
poses a threat to human development, which has resulted in global political commitments …

… Perros P, Colley S, Boelaert K, Evans C, Evans RM, Gerrard GE, Gilbert JA, Harrison B,
Johnson SJ, Giles TE, Moss L, Lewington V, Newbold KL, Taylor J, Thakker RV, Watkinson J …

BACKGROUND School climate has been linked to multiple student behavioral, academic,
health, and social‐emotional outcomes. The US Department of Education ( USDOE ) …

The tumor microenvironment (TME) influences cancer progression and therapy response.
Therefore, understanding what regulates the TME immune compartment is vital. Here we …

Objective To evaluate screening for chromosomal defects by a combination of fetal nuchal
translucency thickness and maternal age. Design A prospective multicentre screening study …

Se is an essential element for animals. In man low dietary Se intakes are associated with
health disorders including oxidative stress-related conditions, reduced fertility and immune …

A variety of species of bacteria are known to colonize human tumours 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8
, 9 , 10 – 11 , proliferate within them and modulate immune function, which ultimately affects …