User profiles for Sandra Porter

Sandra Porter

President, Digital World Biology
Verified email at digitalworldbiology.com
Cited by 788

The virD operon of Agrobacterium tumefaciens encodes a site-specific endonuclease

MF Yanofsky, SG Porter, C Young, LM Albright… - Cell, 1986 - cell.com
Results After cocultivation of Agrobacterium with plant cells, a nick is introduced at unique
and identical locations within the 24 bp direct repeats flanking the T-DNA (Albright et al., …

The MedSafer study—electronic decision support for deprescribing in hospitalized older adults: a cluster randomized clinical trial

…, L Papillon-Ferland, L Pilote, S Porter… - JAMA internal …, 2022 - jamanetwork.com
Importance Scalable deprescribing interventions may reduce polypharmacy and the use of
potentially inappropriate medications (PIMs); however, few studies have been large enough …

A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels

…, JC Souto, JM Peralta, T Smith, J Blangero, S Porter… - Blood, 2007 - ashpublications.org
Plasma factor VIII coagulant activity (FVIII:C) level is a highly heritable quantitative trait that
is strongly correlated with thrombosis risk. Polymorphisms within only 1 gene, the ABO blood-…

The MedSafer study: a controlled trial of an electronic decision support tool for deprescribing in acute care

…, R Tamblyn, R Whitty, S Porter… - Journal of the …, 2019 - Wiley Online Library
OBJECTIVES Polypharmacy is common, costly, and harmful for hospitalized older adults.
Scalable strategies to reduce the burden of potentially inappropriate medications (PIMs) are …

Bioinformatics education in high school: implications for promoting science, technology, engineering, and mathematics careers

…, EA Sanders, KA Peterson, SG Porter… - CBE—Life Sciences …, 2013 - Am Soc Cell Biol
We investigated the effects of our Bio-ITEST teacher professional development model and
bioinformatics curricula on cognitive traits (awareness, engagement, self-efficacy, and …

COVID‐SAFER: deprescribing guidance for hydroxychloroquine drug interactions in older adults

…, S Elsayed, PE Wu, K Battu, S Porter… - Journal of the …, 2020 - Wiley Online Library
BACKGROUND/OBJECTIVES Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
infection causes high morbidity and mortality in older adults with chronic illnesses. …

[HTML][HTML] Idiopathic pulmonary fibrosis: a review of disease, pharmacological, and nonpharmacological strategies with a focus on symptoms, function, and health …

D Rozenberg, N Sitzer, S Porter, A Weiss… - Journal of Pain and …, 2020 - Elsevier
Despite several advances in treatment, idiopathic pulmonary fibrosis (IPF) remains a
progressive, symptomatic, and terminal disease in patients not suitable for lung transplantation. …

Comparative safety and tolerability of endothelin receptor antagonists in pulmonary arterial hypertension

M Aversa, S Porter, J Granton - Drug Safety, 2015 - Springer
Pulmonary arterial hypertension (PAH) is a condition that leads to progressive right heart
failure and death unless recognized and treated early. Endothelin, a potent endogenous …

Characterizing multi-omic data in systems biology

CE Mason, SG Porter, TM Smith - Systems Analysis of Human Multigene …, 2013 - Springer
In today’s biology, studies have shifted to analyzing systems over discrete biochemical
reactions and pathways. These studies depend on combining the results from scores of …

[HTML][HTML] Chronic obstructive pulmonary disease: a palliative medicine review of the disease, its therapies, and drug interactions

A Weiss, S Porter, D Rozenberg, E O'Connor… - Journal of Pain and …, 2020 - Elsevier
Despite significant advances in treatment, chronic obstructive pulmonary disease (COPD)
remains a chronic and progressive disease that frequently leads to premature mortality. COPD …