Donanemab in early symptomatic Alzheimer disease: the TRAILBLAZER-ALZ 2 randomized clinical trial

…, E Grigsby, D Grosz, K Hafner, D Hart, S Henein… - Jama, 2023 - jamanetwork.com
Importance There are limited efficacious treatments for Alzheimer disease. Objective To assess
efficacy and adverse events of donanemab, an antibody designed to clear brain amyloid …

Screening for atrial fibrillation in the older population: a randomized clinical trial

…, AP Benz, JA Wong, F Merali, S Henein… - JAMA …, 2021 - jamanetwork.com
Importance Atrial fibrillation (AF) is a major cause of preventable strokes. Screening asymptomatic
individuals for AF may increase anticoagulant use for stroke prevention. Objective To …

Effectiveness of a novel ω-3 krill oil agent in patients with severe hypertriglyceridemia: a randomized clinical trial

…, A Frechette, P Dzongowski, S Henein… - JAMA network …, 2022 - jamanetwork.com
Importance Intense interest exists in novel ω-3 formulations with high bioavailability to reduce
blood triglyceride (TG) levels. Objective To determine the phase 3 efficacy and safety of a …

[HTML][HTML] Antibody persistence and booster response in adolescents and young adults 4 and 7.5 years after immunization with 4CMenB vaccine

…, F de Looze, H Marshall, P Richmond, S Henein… - Vaccine, 2019 - Elsevier
Background Data on duration of protection against invasive meningococcal disease post-vaccination
with the recombinant, 4-component, meningococcal serogroup B vaccine (4CMenB…

[HTML][HTML] Is screening for atrial fibrillation in Canadian family practices cost-effective in patients 65 years and older?

…, C Ramasundarahettige, PA Frydrych, S Henein… - Canadian Journal of …, 2018 - Elsevier
We present an economic evaluation of a recently completed cohort study in which 2054 seniors
were screened for atrial fibrillation (AF) in 22 Canadian family practices. Using a Markov …

Diagnostic accuracy and yield of screening tests for atrial fibrillation in the family practice setting: a multicentre cohort study

…, PA Frydrych, S Henein… - … Open Access Journal, 2018 - cmajopen.ca
Background: Detection of undiagnosed or undertreated (“actionable”) atrial fibrillation could
increase the use of appropriate oral anticoagulant therapy and reduce the risk of stroke. We …

Two phase 3 trials of dupilumab versus placebo in atopic dermatitis

…, T Vlaeva, A Alavi, G Gauvreau, S Henein… - NEW ENGLAND …, 2016 - ricerca.unich.it
BACKGROUND Dupilumab, a human monoclonal antibody against interleukin-4 receptor
alpha, inhibits signaling of interleukin-4 and interleukin-13, type 2 cytokines that may be …

152. Protective Antibody Levels 7.5 Years After Primary Vaccination in Adolescence With a Recombinant, 4-Component, Meningococcal Serogroup B Vaccine …

…, H Marshall, P Richmond, S Henein… - Open Forum …, 2018 - academic.oup.com
Background 4CMenB has been shown to be immunogenic with an acceptable safety profile
in infants and young adolescents. However, no data on long-term persistence after primary …

[PDF][PDF] 154. Diagnosis and Genotyping of Coxiella burnetii Causing Endocarditis in a Patient With Prosthetic Pulmonary Valve Replacement (PVR) Using Next …

M Kondo, S Dalai, L Westblade… - Open Forum …, 2018 - pdfs.semanticscholar.org
Conclusion. PCV13 was effective in preventing IPD caused by PCV13 types when excluding
type 3; no effectiveness was demonstrated against serotype 3. Disclosures. W. Schaffner, …

[PDF][PDF] 153. The Effect of Timing of Tetanus–Diphtheria and Pertussis Vaccine Administration in Pregnancy on The Avidity of Pertussis Antibodies

BA Raya, M Giles, T Kollmann… - Open Forum …, 2018 - pdfs.semanticscholar.org
Conclusion. PCV13 was effective in preventing IPD caused by PCV13 types when excluding
type 3; no effectiveness was demonstrated against serotype 3. Disclosures. W. Schaffner, …