The use of data from the real world to address clinical and policy-relevant questions that
cannot be answered using data from clinical trials is garnering increased interest. Indeed, data …

Importance Recent data have suggested that disease biology and outcome of colon cancer
may differ between right-sided and left-sided tumors. However, the literature on the …

Introduction The incidence of colorectal cancer in young patients has been increasing. We
evaluated whether the disease characteristics, management, and outcomes of patients with …

Context Considerable advances have been made in the first-line treatment of metastatic
renal cell carcinoma (mRCC), with immunotherapy-based combinations including …

BACKGROUND Clinical trials have established surgical resection and adjuvant chemotherapy
(ACT) as the standard management for stage III colon cancer; however, the extent to …

Background Intimidation and harassment (I&H) have been longstanding problems in residency
training. These behaviours continue to be prevalent, as evidenced by the 2012 Canadian …

Background Uptake of perioperative chemotherapy for muscle-invasive bladder cancer (MIBC)
has been historically poor. We describe contemporary use of neoadjuvant (NACT) and …

Background Cancer patients’ attitudes toward progression-free survival (PFS) gains offered
by treatment are not well understood, particularly in the absence of overall survival (OS) …

Background The global cancer burden falls disproportionately on low and middle-income
countries (LMICs). One significant barrier to adequate cancer control in these countries is the …

BACKGROUND Treatment guidelines for early‐stage testicular cancer have increasingly
recommended de‐escalation of therapy with surveillance strategies. This study was designed …