Importance Physicians self-report high levels of symptoms of anxiety and depression, and
surveys suggest these symptoms have been exacerbated by the COVID-19 pandemic. …

Rationale & Objective Patients with chronic kidney disease (CKD) may be at increased risk
for cancer. CKD may also be associated with worse cancer outcomes. This study examined …

BACKGROUND: Regulatory agencies warn about the risk of acute kidney injury (AKI) after
the initiation of sodium-glucose cotransporter-2 (SGLT2) inhibitors. Our objective was to …

Background AKI is common during pediatric hospitalizations and associated with adverse
short-term outcomes. However, long-term outcomes among survivors of pediatric AKI who …

The Autobiographical Interview (AI) separates internal (episodic) and external (non-episodic)
details from transcribed protocols using an exhaustive and reliable scoring system. While …

Results After weighting, we identified a total of 38,994 new users of a SGLT2 inhibitor and
37,449 new users of a DPP-4 inhibitor and observed a total of 342 fractures at 180 days and …

Background The Coronavirus Disease 2019 (COVID–19) pandemic has exacerbated mental
health challenges among physicians and non–physicians. However, it is unclear if the …

Background Older adults with chronic kidney disease (CKD) are at heightened risk for
polypharmacy. We examined potentially inappropriate prescribing in this population and whether …

Rationale & Objective Acute kidney injury (AKI) is common among hospitalized children and
is associated with increased hospital length of stay and costs. However, there are limited …

Results Each direct oral anticoagulant was associated with a significantly lower risk of AKI
compared with warfarin (weighted hazard ratio, 0.65; 95% confidence interval, 0.53 to 0.80 for …