User profiles for Nicolas Beaudet
 | Nicolas BeaudetAdjunct professor, department of anesthesiology, Université de Sherbrooke Verified email at usherbrooke.ca Cited by 2411 |
Spinal CCL2 pronociceptive action is no longer effective in CCR2 receptor antagonist‐treated rats
…, W Rostene, P Kitabgi, N Beaudet… - Journal of …, 2008 - Wiley Online Library
A better understanding of the mechanisms linked to chemokine pronociceptive effects is
essential for the development of new strategies to better prevent and treat chronic pain. Among …
essential for the development of new strategies to better prevent and treat chronic pain. Among …
Increased anxiety-like behaviors in rats experiencing chronic inflammatory pain
For many patients, chronic pain is often accompanied, and sometimes amplified, by co-morbidities
such as anxiety and depression. Although it represents important challenges, the …
such as anxiety and depression. Although it represents important challenges, the …
[HTML][HTML] Combination of high-fat/high-fructose diet and low-dose streptozotocin to model long-term type-2 diabetes complications
…, F Lizotte, A Kessai, K Kirby, K Belleville, N Beaudet… - Scientific Reports, 2018 - nature.com
The epidemic of type 2 diabetes mellitus (T2DM) is fueled by added fructose consumption.
Here, we thus combined high-fat/high-fructose diet, with multiple low-dose injections of …
Here, we thus combined high-fat/high-fructose diet, with multiple low-dose injections of …
Neurochemokines: a menage a trois providing new insights on the functions of chemokines in the central nervous system
J. Neurochem. (2011) 118, 680–694. Abstract Recent observations suggest that besides
their role in the immune system, chemokines have important functions in the brain. There is a …
their role in the immune system, chemokines have important functions in the brain. There is a …
[HTML][HTML] Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties
M Demeule, N Beaudet, A Régina… - The Journal of …, 2014 - Am Soc Clin Investig
Neurotensin (NT) has emerged as an important modulator of nociceptive transmission and
exerts its biological effects through interactions with 2 distinct GPCRs, NTS1 and NTS2. NT …
exerts its biological effects through interactions with 2 distinct GPCRs, NTS1 and NTS2. NT …
Elucidation of the structure–activity relationships of apelin: influence of unnatural amino acids on binding, signaling, and plasma stability
…, H Tremblay, F Karadereye, N Beaudet… - …, 2012 - Wiley Online Library
Apelin is the endogenous ligand of the APJ receptor, a member of the G‐protein‐coupled
receptor family. The apelin–APJ complex has been detected in many tissues and is emerging …
receptor family. The apelin–APJ complex has been detected in many tissues and is emerging …
Weight bearing evaluation in inflammatory, neuropathic and cancer chronic pain in freely moving rats
…, MA Dansereau, L Doré-Savard, N Beaudet… - Physiology & …, 2011 - Elsevier
Preclinical pain assessment remains a key step for the development of new and potent
painkillers. Significant progress in pain evaluation has been achieved with the development of …
painkillers. Significant progress in pain evaluation has been achieved with the development of …
The chemokine CCL2 increases Nav1. 8 sodium channel activity in primary sensory neurons through a Gβγ-dependent mechanism
…, J Van Steenwinckel, N Beaudet… - Journal of …, 2011 - Soc Neuroscience
Changes in function of voltage-gated sodium channels in nociceptive primary sensory neurons
participate in the development of peripheral hyperexcitability that occurs in neuropathic …
participate in the development of peripheral hyperexcitability that occurs in neuropathic …
Developmental motor deficits induced by combined fetal exposure to lipopolysaccharide and early neonatal hypoxia/ischemia: a novel animal model for cerebral palsy …
A critical issue in animal models of perinatal brain injury is to adapt the pertinent
pathophysiological scenarios to their corresponding developmental window in order to induce …
pathophysiological scenarios to their corresponding developmental window in order to induce …
Digital health interventions for the management of mental health in people with chronic diseases: a rapid review
Objective Determine the effectiveness of digital mental health interventions for individuals with
a concomitant chronic disease. Design We conducted a rapid review of systematic reviews…
a concomitant chronic disease. Design We conducted a rapid review of systematic reviews…