User profiles for Michael Zappitelli

Michael Zappitelli

Pediatric Nephrologist at The Hospital for Sick Children; Senior Scientist for Child Health
Verified email at sickkids.ca
Cited by 15591

Renal replacement therapy in critically ill patients receiving extracorporeal membrane oxygenation

…, DS Cooper, BC Bridges, M Zappitelli… - Clinical Journal of the …, 2012 - journals.lww.com
Extracorporeal membrane oxygenation (ECMO) is a lifesaving procedure used in neonates,
children, and adults with severe, reversible, cardiopulmonary failure. On the basis of single-…

Canadian Society of Nephrology commentary on the 2012 KDIGO clinical practice guideline for acute kidney injury

…, JP LaFrance, C Rigatto, R Wald, M Zappitelli… - American Journal of …, 2013 - Elsevier
Conclusion The KDIGO AKI guideline represents an important advance in synthesizing evidence
about the identification and management of AKI; however, it also highlights many areas …

Biomarkers of acute kidney injury in children: discovery, evaluation, and clinical application

Z Al-Ismaili, A Palijan, M Zappitelli - Pediatric Nephrology, 2011 - Springer
Acute kidney injury (AKI) in children is associated with increased mortality and prolonged
length of hospital stay and may also be associated with long-term chronic kidney disease …

The outcome of neutrophil gelatinase-associated lipocalin-positive subclinical acute kidney injury: a multicenter pooled analysis of prospective studies

…, JL Koyner, P Murray, M Zappitelli… - Journal of the American …, 2011 - jacc.org
Objectives : The aim of this study was to test the hypothesis that, without diagnostic changes
in serum creatinine, increased neutrophil gelatinase-associated lipocalin (NGAL) levels …

Fluid overload and mortality in children receiving continuous renal replacement therapy: the prospective pediatric continuous renal replacement therapy registry

SM Sutherland, M Zappitelli, SR Alexander… - American journal of …, 2010 - Elsevier
BACKGROUND: Critically ill children with hemodynamic instability and acute kidney injury
often develop fluid overload. Continuous renal replacement therapy (CRRT) has emerged as …

Postoperative biomarkers predict acute kidney injury and poor outcomes after adult cardiac surgery

…, P Devarajan, UD Patel, M Zappitelli… - Journal of the …, 2011 - journals.lww.com
Acute kidney injury (AKI) is a frequent complication of cardiac surgery and increases morbidity
and mortality. The identification of reliable biomarkers that allow earlier diagnosis of AKI …

Postoperative biomarkers predict acute kidney injury and poor outcomes after pediatric cardiac surgery

CR Parikh, P Devarajan, M Zappitelli… - Journal of the …, 2011 - journals.lww.com
Acute kidney injury (AKI) occurs commonly after pediatric cardiac surgery and associates
with poor outcomes. Biomarkers may help the prediction or early identification of AKI, …

[HTML][HTML] Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study

M Zappitelli, KK Washburn, AA Arikan, L Loftis, Q Ma… - Critical Care, 2007 - Springer
Introduction Serum creatinine is a late marker of acute kidney injury (AKI). Urine neutrophil
gelatinase-associated lipocalin (uNGAL) is an early marker of AKI, where the timing of kidney …

Fluid overload is associated with impaired oxygenation and morbidity in critically ill children

AA Arikan, M Zappitelli, SL Goldstein… - Pediatric critical care …, 2012 - journals.lww.com
Objective: Investigate the association between fluid overload and oxygenation while controlling
for severity of illness by daily Pediatric Logistic Organ Dysfunction scores. Design and …

Incidence, risk factors, and outcomes of acute kidney injury after pediatric cardiac surgery: a prospective multicenter study

S Li, CD Krawczeski, M Zappitelli… - Critical care …, 2011 - journals.lww.com
Objective: To determine the incidence, severity, and risk factors of acute kidney injury in
children undergoing cardiac surgery for congenital heart defects. Design: Prospective …