User profiles for Michael Jacobson

Michael J Jacobson

University of Sydney
Verified email at sydney.edu.au
Cited by 10440

[HTML][HTML] Programmed cell death in animal development

MD Jacobson, M Weil, MC Raff - cell, 1997 - cell.com
Programmed cell death (PCD) occurs during the development of all animals that have been
studied, but only recently has its molecular basis been discovered. In this review, we briefly …

Cognitive flexibility, constructivism, and hypertext: Random access instruction for advanced knowledge acquisition in ill-structured domains

RJ Spiro, PJ Feltovich, MJ Jacobson… - Constructivism in …, 2012 - taylorfrancis.com
At a party where I work, we were drinking some homemade beer. As we shifted back and
forth between two different batches, it became clear that one of the batches was significantly …

Programmed cell death and the control of cell survival: lessons from the nervous system

…, JF Burne, HS Coles, Y Ishizaki, MD Jacobson - Science, 1993 - science.org
During the development of the vertebrate nervous system, up to 50 percent or more of many
types of neurons normally die soon after they form synaptic connections with their target cells…

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA

MD Jacobson, JF Burne, MP King, T Miyashrta… - Nature, 1993 - nature.com
WHEN the mammalian proto-oncogene bcl-2 is overexpressed it can protect various types of
cells both from normal and from experimentally induced apoptosis 1–6 A but the molecular …

Reactive oxygen species and programmed cell death

MD Jacobson - Trends in biochemical sciences, 1996 - cell.com
Bcl-2 is a proto-oncoprotein with apparently one function—to suppress programmed cell
death (PCD)—yet how it does so remains a mystery. Several authors have proposed that Bcl-2 …

Complex systems in education: Scientific and educational importance and implications for the learning sciences

MJ Jacobson, U Wilensky - The Journal of the learning sciences, 2006 - Taylor & Francis
The multidisciplinary study of complex systems in the physical and social sciences over the
past quarter of a century has led to the articulation of important new conceptual perspectives …

Halting the obesity epidemic: a public health policy approach.

M Nestle, MF Jacobson - Public health reports, 2000 - ncbi.nlm.nih.gov
Traditional ways of preventing and treating overweight and obesity have almost invariably
focused on changing the behavior of individuals, an approach that has proven woefully …

Hypertext learning environments, cognitive flexibility, and the transfer of complex knowledge: An empirical investigation

MJ Jacobson, RJ Spiro - Journal of educational computing …, 1995 - journals.sagepub.com
Although the use of hypertext systems for learning complex knowledge has been attracting
recent attention, we currently have poor theoretical and research perspectives from which to …

Small taxes on soft drinks and snack foods to promote health.

MF Jacobson, KD Brownell - American journal of public health, 2000 - ncbi.nlm.nih.gov
… Requests for reprints should be sent to Michael F. Jacobson, PhD, Center for Science in the
Public Interest, 1875 Connecticut … MF Jacobson did most of the research for this paper. MF …

Programmed cell death and Bcl-2 protection in very low oxygen

MD Jacobson, MC Raff - Nature, 1995 - nature.com
PROGRAMMED cell death (PCD) is a fundamental feature of animal cells 1 , but the mechanism
remains unknown. Similarly, the Bcl-2 oncoprotein can suppress PCD in a variety of cell …