Context.—Clinical trials have established the efficacy of antiretroviral therapy with double-
and triple-drug regimens for individuals infected with the human immunodeficiency virus (HIV)…

Objective: To describe prevalence and incidence of HIV-1, hepatitis C virus (HCV) and risk
behaviours in a prospective cohort of injecting drug users (IDU). Setting: Vancouver, which …

Background. Osteoporosis develops in women with estrogen deficiency and amenorrhea
who lose bone at an accelerated rate. It Is not known to what extent bone loss differs between …

Context.—In British Columbia, human immunodeficiency virus (HIV)–infected persons eligible
for antiretroviral therapy may receive it free but the extent to which HIV-infected injection …

Background. Advances in molecular genetics have led to the development of tests that can
predict the risk of inheriting the genes for several adult-onset diseases. However, the …

Objectives: The explosive and ongoing injecting drug use-related HIV-1 epidemic in Vancouver
continues to receive international attention. This study was conducted to determine how …

Background Studies in Europe have suggested that injectable diacetylmorphine, the active
ingredient in heroin, can be an effective adjunctive treatment for chronic, relapsing opioid …

BACKGROUND: The efficacy of triple-drug antiretroviral regimens in the treatment of patients
infected with HIV has been established in several randomized clinical trials. However, the …

We determined whether availability of new antiretroviral treatments has had any impact on
the rate of death for people with HIV-1 infection. Distribution of antiretroviral drugs in British …

Background: Many injection drug users (IDUs) seek care at emergency departments and
some require hospital admission because of late presentation in the course of their illness. We …