Background Respiratory failure due to lung immaturity is a major cause of mortality in preterm
infants. Although the use of intermittent positive pressure ventilation (IPPV) in neonates …

Importance Clinicians, patients, and policy makers rely on published results from clinical
trials to help make evidence-informed decisions. To critically evaluate and use trial results, …

ContextChanges in the prevalence of chronic health conditions in childhood have considerable
societal consequences for health care planning and for employment. To obtain valid and …

… Dekker (Medical Center University Leyden) and Martin Prins (Dept. Clinical Epidemiology
& Biostatistics, Academic Medical Center, Amsterdam) both provided epidemiological advice. …

There are no guidelines available for diagnostic studies in patients with mental retardation (MR)
established in an evidence-based manner. Here we report such study, based on …

To reassess the relations between postulated risk factors and seizure recurrence after a first
febrile seizure (FS), the individual data from five follow-up studies that used similar …

BACKGROUND AND OBJECTIVE: Hypoxic-ischemic encephalopathy (HIE) after perinatal
asphyxia in term neonates causes long-term neurologic sequelae or death. A reliable …

Background Mucopolysaccharidosis type I (MPS I) is a lysosomal storage disorder that results
in the accumulation of glycosaminoglycans causing progressive multi-organ dysfunction. …

OBJECTIVE. Our goal was to assess the effect of episodes of neonatal hypoglycemia on
subsequent neurodevelopment. METHODS. We searched Medline and Embase for cohort …

Background Febrile seizures occurring in a child older than one month during an episode of
fever affect 2‐4% of children in Great Britain and the United States and recur in 30%. Rapid‐…