Introduction: Opioid-related mortality appears to be increasing in Canada. We examined the
true extent of the problem and the impact of the introduction of long-acting oxycodone. …

… , Marco LA Sivilotti associate professor of emergency medicine and of pharmacology and
toxicology2, Michael J Bullard professor of emergency medicine3, Marcel Émond assistant …

Objective. —To validate a previously derived decision rule for the use of radiography in
patients with acute knee injury. Design. —Prospectively administered survey. Setting. —…

Importance Three clinical decision rules were previously derived to identify patients with
headache requiring investigations to rule out subarachnoid hemorrhage. Objective To assess …

Background Observational studies have suggested that accelerated surgery is associated
with improved outcomes in patients with a hip fracture. The HIP ATTACK trial assessed …

Context. —The Ottawa Knee Rule is a previously validated clinical decision rule that was
developed to allow physicians to be more selective and efficient in their use of plain …

Objective To identify high risk clinical characteristics for subarachnoid haemorrhage in
neurologically intact patients with headache. Design Multicentre prospective cohort study over …

Background Spontaneous subarachnoid hemorrhage ( SAH ) is a rare, but serious etiology
of headache. The diagnosis of SAH is especially challenging in alert, neurologically intact …

Importance Suicide is the tenth leading cause of death in the United States, and its rate has
risen by 16% in the past decade. Deliberate self-poisoning is the leading method of …

Background: Syncope can be caused by serious conditions not evident during initial
evaluation, which can lead to serious adverse events, including death, after disposition from the …