Background Although reports in adults suggest that breaks in sedentary time are associated
with reduced cardiometabolic risk, these findings have yet to be replicated in children. …

Background Few studies consider how risk factors within multiple levels of influence operate
synergistically to determine childhood obesity. We used recursive partitioning analysis to …

The objective of this study was to examine the combined associations between time spent
in moderate- to vigorous-intensity physical activity (MVPA) and time spent sedentary in …

Familial hypercholesterolemia (FH) is the most common monogenic disorder causing premature
atherosclerotic cardiovascular disease. It affects 1 in 250 individuals worldwide, and of …

The epidemic rise in the prevalence of obesity and in particular, paediatric obesity has led to
concerns that the complications of excess adiposity may well reverse the favourable trends …

Importance Despite extensive evidence showing that lifestyle habits play a critical role in
preventing or delaying the onset of type 2 diabetes in adults, little is known regarding the impact …

Little is known about longitudinal associations between added sugar consumption (solid and
liquid sources) and glucose-insulin homeostasis among youth. Caucasian children (8–10 y…

Background Qualitative studies in type 1 diabetes indicate that visibility of diabetes supplies,
self-care, and hypoglycemia symptoms are associated with stigma and suboptimal …

Objectives To identify the main barriers to active lifestyles in children with type 1 diabetes
based on known barriers in adults with type 1 diabetes. Methods Children with type 1 diabetes (…

OBJECTIVE: To assess the efficacy and safety of metformin via systematic review. DATA
SOURCES: Data sources included PubMed, Embase, the Cochrane Library, Scopus, and …