This study was carried out to determine whether the minimal important difference, in evaluative
quality of life instruments which use a 7-point scale, is similar across individual domains …

When little or no data directly comparing two treatments are available, investigators often
rely on indirect comparisons from studies testing the treatments against a control or placebo. …

The Paediatric Asthma Quality of Life Questionnaire contains 23 items that children with
asthma have identified as troublesome in their daily lives. The aim was to evaluate the …

Background: Understanding the risk factors for ventilator-associated pneumonia can help to
assess prognosis and devise and test preventive strategies. Objective: To examine the …

Study Design In an 8-wk unblinded single cohort study, patients with adequately controlled
asthma symptoms continued on their established treatment regimens. Patients whose …

Purpose. —To resolve discrepancies in previous systematic overviews and provide estimates
of the effect of stress ulcer prophylaxis on gastrointestinal bleeding, pneumonia, and …

The need to measure the impact of treatments on health related quality of life has led to a
rapid increase in the variety of instruments available and in their use as measures of outcome …

Objective: To examine the association between cognitive function and dementia with
vitamin D concentration in adults. Methods: Five databases were searched for English-language …

Canadians are living longer, and older persons are making up a larger share of the population
(14% in 2006, projected to rise to 20% by 2021). The Canadian Longitudinal Study on …

Objective To estimate the mortality and length of stay in the intensive care unit (ICU) attributable
to clinically important gastrointestinal bleeding in mechanically ventilated critically ill …