OBJECTIVE: Liver biopsies are performed in patients with primary sclerosing cholangitis (PSC)
to stage disease and to rule out coexisting liver disease. The purpose of this study was to …

OBJECTIVES: Screening tools to determine which outpatients with cirrhosis are at highest
risk forunplannedhospitalization are lacking. Frailty is a novel prognostic factor but …

BACKGROUND: Although most patients with autoimmune hepatitis (AIH) respond to treatment
with prednisone and/or azathioprine, some patients are intolerant or refractory to standard …

Recurrence of hepatitis C virus (HCV) infection after liver transplantation (LT) is almost
universal. However, variables that hasten the progression of allograft injury have not been fully …

OBJECTIVES: Rituximab, an anti-CD20 monoclonal antibody that selectively depletes B
cells, has shown promise in autoantibody-associated, immune-mediated disorders. As …

The treatment of hepatitis C has become safer, better tolerated and more effective owing to
the availability of direct-acting antivirals for nearly all patients; this guideline advocates …

The recent epidemiology and outcomes of primary biliary cirrhosis (PBC) in North America
are incompletely described, partly due to difficulties in case ascertainment. In light of their …

Background. Orthotopic liver transplantation (OLT) stresses the cardiovascular system, and
cardiac complications after OLT are common. Methods. Hundred ninety-seven patients (≥ …

BACKGROUND & AIMS: The Model for End-Stage Liver Disease (MELD) allocation system
for liver transplantation (LT) may present a disadvantage for women by including serum …

Chronic hepatitis C remains a significant medical and economic burden in Canada,
affecting nearly 1% of the population. Since the last Canadian consensus conference on the …