User profiles for Kelly Metcalfe

Kelly Metcalfe

University of Toronto
Verified email at utoronto.ca
Cited by 10374

[PDF][PDF] Contralateral Breast Cancer in BRCA1 and BRCA2 Mutation Carriers

K Metcalfe, HT Lynch, P Ghadirian… - Journal of Clinical …, 2004 - scholar.archive.org
Purpose To estimate the risk of contralateral breast cancer in BRCA1 and BRCA2 carriers
after diagnosis and to determine which factors are predictive of the risk of a second primary …

[HTML][HTML] Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation

…, HT Lynch, S Neuhausen, KA Metcalfe… - Journal of Clinical …, 2014 - ncbi.nlm.nih.gov
Purpose The purposes of this study were to estimate the reduction in risk of ovarian, fallopian
tube, or peritoneal cancer in women with a BRCA1 or BRCA2 mutation after oophorectomy…

International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers

KA Metcalfe, D Birenbaum‐Carmeli… - … journal of cancer, 2008 - Wiley Online Library
Several options for cancer prevention are available for women with a BRCA1 or BRCA2
mutation, including prophylactic surgery, chemoprevention and screening. The authors report …

Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families

…, W McKinnon, A Meindl, K Metcalfe… - Journal of clinical …, 2020 - ascopubs.org
PURPOSE To estimate age-specific relative and absolute cancer risks of breast cancer and
to estimate risks of ovarian, pancreatic, male breast, prostate, and colorectal cancers …

Estrogen Receptor Status in BRCA1- and BRCA2-Related Breast Cancer: The Influence of Age, Grade, and Histological Type

WD Foulkes, K Metcalfe, P Sun, WM Hanna… - Clinical Cancer …, 2004 - AACR
Purpose: BRCA1-related breast cancers are more frequently estrogen receptor (ER) negative
than are either BRCA2-related or nonhereditary breast cancers. The relationship between …

Contralateral mastectomy and survival after breast cancer in carriers of BRCA1 and BRCA2 mutations: retrospective analysis

K Metcalfe, S Gershman, P Ghadirian, HT Lynch… - Bmj, 2014 - bmj.com
Objective To compare the survival rates of women with BRCA associated breast cancer who
did and did not undergo mastectomy of the contralateral breast. Design Retrospective …

[PDF][PDF] Screening for founder mutations in BRCA1 and BRCA2 in unselected Jewish women

KA Metcalfe, A Poll, R Royer, M Llacuachaqui… - J Clin Oncol, 2010 - academia.edu
Purpose There are two mutations in BRCA1 and one mutation in BRCA2 that are present in
up to 2.5% of Ashkenazi Jewish women. Current guidelines for testing stipulate that a …

[HTML][HTML] Using a mobile app for monitoring post-operative quality of recovery of patients at home: a feasibility study

…, J Theodoropoulos, KA Metcalfe - JMIR mHealth and …, 2015 - mhealth.jmir.org
Background: Mobile apps are being viewed as a new solution for post-operative monitoring
of surgical patients. Mobile phone monitoring of patients in the post-operative period can …

Predictors of Contralateral Prophylactic Mastectomy in Women With a BRCA1 or BRCA2 Mutation: The Hereditary Breast Cancer Clinical Study Group

KA Metcalfe, J Lubinski, P Ghadirian… - Journal of Clinical …, 2008 - ascopubs.org
Purpose To evaluate the rate of prophylactic contralateral mastectomy in an international
cohort of women with hereditary breast cancer and to evaluate the predictors of uptake of …

A comparison of psychological response, body image, sexuality, and quality of life between immediate and delayed autologous tissue breast reconstruction: a …

…, CB Novak, SOP Hofer, KA Metcalfe - Plastic and …, 2016 - journals.lww.com
Background: This is the first study to use generic distress, cancer-specific, and procedure-specific
measures to prospectively evaluate psychological responses, body image, sexuality, …