Obesity is now reaching epidemic proportions in both developed and developing countries
and is affecting not only adults but also children and adolescents. Over the last 20 years, …

BACKGROUND: Several estimates of the risk of progression to diabetes in people with
impaired fasting glucose (IFG) or impaired glucose tolerance (IGT) have been reported. …

Mitochondrial uncoupling protein 1 (UCP1) is enriched within interscapular brown adipose
tissue (iBAT) and beige (also known as brite) adipose tissue 1 , 2 , but its thermogenic …

Background There is an increasing recognition of the relationship between mental illness
and obesity in the pediatric population. Our objective was to explore the individual, biological …

An important association exists between obesity and mental illness that impacts all aspects
of an individual's quality of life. This association can begin early in the developmental …

The American Medical Association recently recognized obesity as both an illness and a
leading cause of preventable death and chronic disease. This association is not only linked to …

Adults born preterm at very low birth weight (VLBW; <1500 g) have higher blood pressure
than those born at term. It is not known whether all VLBW adults are at risk or whether higher …

Obesity results from a caloric imbalance between energy intake, absorption and expenditure.
In both rodents and humans, diet-induced thermogenesis contributes to energy …

Early life microbial colonization and succession is critically important to healthy development
with impacts on metabolic and immunologic processes throughout life. A longitudinal …

BACKGROUND: Young adults born with extreme prematurity have increased blood pressure
and insulin resistance. This study documents their metabolic health as they enter their …