Alterations in white matter (WM) microstructure have been implicated in the pathophysiology
of major depressive disorder (MDD). However, previous findings have been inconsistent, …

Background Childhood maltreatment is a leading environmental risk factor for an unfavourable
course of disease in major depressive disorder. Both maltreatment and major depressive …

Background Greater understanding of international cancer survival differences is needed.
We aimed to identify predictors and consequences of cancer diagnosis through emergency …

Adolescent-onset major depressive disorder (MDD) is associated with an increased risk of
recurrent depressive episodes, suicidal behaviors, and psychiatric morbidity throughout the …

Objective The absence of neurobiological diagnostic markers of bipolar disorder ( BD ) leads
to its frequent misdiagnosis as unipolar depression ( UD ). We investigated if changes in …

Distinguishing bipolar disorder from major depressive disorder is a major challenge in
psychiatric treatment. Consequently, there has been growing interest in identifying neuronal …

Importance More than half of all patients with major depressive disorder (MDD) experience
a relapse within 2 years after recovery. It is unclear how relapse affects brain morphologic …

Alterations in regional subcortical brain volumes have been investigated as part of the
efforts of an international consortium, ENIGMA, to identify reliable neural correlates of major …

Obesity has been associated with a variety of neurobiological alterations. Recent neuroimaging
research has pointed to the relevance of brain structural and functional alterations in the …

Objective Learning and memory performance have been reported to be impaired in patients
with Major Depressive Disorder (MDD). Impairments are associated with diminished …