Age-related macular degeneration (AMD) is the most frequent cause of irreversible
blindness in the elderly in developed countries. Our previous studies implicated activation of …

Background Blinatumomab, a bispecific monoclonal antibody construct that enables CD3-positive
T cells to recognize and eliminate CD19-positive acute lymphoblastic leukemia (ALL) …

Age-related macular degeneration (AMD) is the most common form of irreversible blindness
in developed countries 1 , 2 . Variants in the factor H gene (CFH, also known as HF1), which …

Effective treatment options are limited for patients with acute myeloid leukemia (AML) who
cannot tolerate intensive chemotherapy. Adults age ≥18 years with newly diagnosed AML …

We performed a three-phase genome-wide association study (GWAS) using cases and
controls from a genetically isolated population, Ashkenazi Jews (AJ), to identify loci associated …

Background. Variants in the complement factor H gene (CFH) are associated with age‐related
macular degeneration (AMD). CFH and five CFH‐related genes (CFHR1‐5) lie within the …

Drug resistance is a major hurdle in oncology. Responses of acute myeloid leukaemia (AML)
patients to cytarabine (Ara-C)-based therapies are often short lived with a median overall …

Benefiting from recent developments in landscape anthropology, the objective of this
research is to explore the landscape experiences and values of residents of a small city in the …

Students’ mental health has been an increased concern since the outbreak of the COVID-19
pandemic. However, academic outcomes have received very little attention. In this study, …

Introduction: Adults with newly diagnosed acute lymphoblastic leukemia (ALL) can achieve
a high rate of complete remission (CR) with conventional chemotherapy (CC), but frequently …