The past year has witnessed substantial advances in understanding the genetic basis of many
common phenotypes of biomedical importance. These advances have been the result of …

Clefts of the lip and palate are generally divided into two groups, isolated cleft palate and
cleft lip with or without cleft palate, representing a heterogeneous group of disorders affecting …

OBJECTIVE: To examine the association between maternal smoking and non-syndromic
orofacial clefts in infants. METHODS: A meta-analysis of the association between maternal …

Objective: To investigate the frequency of neonatal and later childhood morbidity in children
exposed to antiepileptic drugs in utero. Design: Retrospective population based study. …

The Indian sub-continent remains one of the most populous areas of the world with an
estimated population of 1.1 billion in India alone. This yields an estimated 24.5 million births per …

Although amyotrophic lateral sclerosis (ALS) was identified as a neurological condition 150
years ago, risk factors related to the onset and progression of ALS remain largely unknown. …

Making sense of rapidly evolving evidence on genetic associations is crucial to making
genuine advances in human genomics and the eventual integration of this information in the …

Established guidelines for causal inference in epidemiological studies may be inappropriate
for genetic associations. A consensus process was used to develop guidance criteria for …

Objective To investigate the association between smoking and orofacial clefts in the United
Kingdom. Design Case-control study in which the mother's exposure to tobacco smoke was …

Background: Previous studies have yielded inconsistent results for the effects of periconceptional
multivitamins containing folic acid and of folic acid food fortification on congenital heart …